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重要文件

P1742

Sigma-Aldrich

前白蛋白 来源于人类血浆

lyophilized powder

同義詞:

甲状腺素结合前白蛋白, 甲状腺素运载蛋白

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25
暫時無法取得訂價和供貨情況

生物源

human plasma

品質等級

化驗

≥95% (SDS-PAGE)

形狀

lyophilized powder

技術

immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable

雜質

Infectious agents, tested

溶解度

H2O: soluble 1 mg/mL

&epsilon ;(消光係數)

13.5 at 280 nm at 1%

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... TTR(7276)

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一般說明

人前白蛋白是18号染色体的产物。它是一种血清蛋白,主要在肝脏中合成。[1] 它是一种四聚体蛋白,分子量为55 kDa。人前白蛋白由非共价结合的四个相同的单体(127个氨基酸残基)组成,排列成对称的四面体。[2]

應用

人前白蛋白用于研究肺癌血清中甲状腺素运载蛋白表达的下调。[3]
前白蛋白(来自人血浆)已用作免疫沉淀的阳性对照[4]作为火箭免疫电泳法定量分析脑脊液的参考标准品。[5]

生化/生理作用

人前白蛋白可在类癌瘤中观察到。[1]
前白蛋白水平是营养不良的指示剂,而且可能受到炎症反应调节。[6]在慢性肾衰竭患者的透析期间,它被视为蛋白质能量营养不良(PEM)的潜在标志物。[7]低水平的前蛋白会导致心脏衰竭(HF)风险提高。[8]

包裝

包装规格基于蛋白含量

外觀

含有磷酸钠和NaCl的冻干粉

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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K Nelson et al.
International journal of cancer, 15(5), 806-814 (1975-05-15)
Spleen cells from BALB/c mice which either bore syngeneic sarcomas or were normal controls were cultured in vitro. The culture supernatants of spleen cells from tumor-bearing mice inhibited (blocked) specific cell-mediated cytotoxicity to the tumor borne by the spleen donor.
Haruki Koike et al.
Journal of neurology, 255(10), 1526-1533 (2008-09-30)
Through the development of gene diagnostic techniques, late-onset transthyretin Met30-associated familial amyloid polyneuropathy (FAP TTR Met30) has been shown to be more prevalent than is generally believed. To examine the electrophysiological features of late-onset FAP TTR Met30 unrelated to endemic
Prealbumin is as important as albumin in the nutritional assessment of hemodialysis patients
Chertow GM, et al.
Kidney International, 58(6), 2512-2517 (2000)
Takashi Ito et al.
Internal medicine (Tokyo, Japan), 45(20), 1173-1175 (2006-11-16)
Previously no functional study has been available for the mechanism of constipation in familial amyloid polyneuropathy (FAP). We performed a gut function test in a 78-year-old woman with transthyretin-type FAP who had severe constipation. The gut function test showed a
J P Hegmann
Behavior genetics, 9(3), 165-175 (1979-05-01)
Behavioral and physiological scores from 697 mice sampled from lines at various times during their response to bidirectional selection for divergent caudal nerve conduction velocity suggest broad-reaching behavioral effects of the gene differences among lines. Sciatic nerve conduction velocity differences

Questions

1–6 of 6 Questions  
  1. How long does prealbumin from human plasma (product P1742) remain stable after being dissolved in water, and at what temperature should this solution be stored?

    1 answer
    1. Stock solutions are stable for up to 2 weeks when stored refrigerated at 4°C and up to 6 months when stored in aliquots at -20°C. Avoid repeated freeze/thaw cycles.

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  2. What is the molecular weight of Product P1742, Prealbumin from human plasma?

    1 answer
    1. The molecular weight has been reported to be 54,980 Daltons. Referece: The Plasma Proteins, 2nd edition (1975) p. 60.

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  3. What is the solubility of Product P1742, Prealbumin from human plasma?

    1 answer
    1. This product is soluble in water at 1mg/mL.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. What is the volume from which Product P1742, Prealbumin from human plasma, is lyophilized from?

    1 answer
    1. The starting volume is lot specific. Please contact Technical Service to obtain the exact volume of your lot of interest.

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  6. What is the purity of Product P1742, Prealbumin from human plasma?

    1 answer
    1. Information about purity can be found on the lot specific certificate of analysis.

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