推薦產品
應用
α2-巨球蛋白用于研究脂蛋白受体介导的血浆淀粉样蛋白-β 外周结合受损,这是阿尔茨海默′病前轻度认知障碍的早期生物标志物。它还用于控制补体激活的经典途径和 MBL 途径。
通过与蛋白酶形成复合物来抑制所有种类的内切蛋白酶。当蛋白酶切割巨球蛋白“诱饵”序列时,巨球蛋白重新排列并捕获蛋白酶。
生化/生理作用
α2-巨球蛋白在血浆和间质液中大量存在。蛋白酶-α2-M 平衡在介导炎症组织破坏中起重要作用。脓毒症、肺气肿、牙周炎、类风湿性关节炎和其他炎症性疾病患者的血清 α2-M 和蛋白酶-α2-M 复合物水平升高,而 α2-M 的氧化失活可能导致炎症期间的组织破坏。
α2-巨球蛋白(α2M)是一种多功能蛋白,是一种广谱蛋白酶抑制剂。α2M 是一种大的同型四聚体糖蛋白(720 kDa),由二硫键连接的二聚体连接,二聚体通过非共价相互作用形成四级结构。α2M 存在于正常血浆中,浓度为 220-230 mg/dl,占总血浆蛋白的 3-5%。
包裝
包装尺寸基于蛋白质含量
外觀
从 0.02 M Tris、0.13 M 甘氨酸、pH 8.0 和 0.08 M 海藻糖中冻干
分析報告
对每个供体的血浆都进行了检测,发现 HIV-1/HIV-2 抗体、HCV 抗体和 HbSAg 抗体均为阴性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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文章
Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.
Uncover properties and applications of the cysteine protease papain and find inhibitors, substrates, and other papain products.
發現半胱氨酸蛋白酶木瓜蛋白酶的特性和應用,並找到抑制劑、底物和其他木瓜蛋白酶產品。
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
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