跳轉至內容
Merck
全部照片(1)

文件

H3536

Sigma-Aldrich

结合柱蛋白 来源于混合人类血浆

≥95% (SDS-PAGE), lyophilized powder

同義詞:

Haptoglobin from human plasma

登入查看組織和合約定價


About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.61

生物源

human plasma (pooled)

品質等級

化驗

≥95% (SDS-PAGE)

形狀

lyophilized powder

技術

activity assay: suitable

溶解度

H2O: soluble 10 mg/mL

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... HP(3240)

尋找類似的產品? 前往 產品比較指南

一般說明

触珠蛋白是一种在正常血浆中发现的 α 2 -球蛋白,浓度为 82-236 mg/dL,占血浆总蛋白的 0.4-2.6%。这种急性期血浆蛋白的单体形式由四条多肽链组成:两条 α链和两个 β链条。
触珠蛋白是一种急性期蛋白,可清除释放到循环中的血红蛋白。结合珠蛋白是与血红蛋白亲和力最高的血浆蛋白,主要在肝脏中表达。

應用

结合珠蛋白用于研究诱导精子顶体反应。暴露于低温会增加它们与无透明带仓鼠卵母细胞的融合率。

生化/生理作用

通过与血浆血红蛋白结合(来自溶血)发挥作用。该复合物通过与巨噬细胞上的 CD163 受体结合,从循环中清除,以挽救铁并防止氧化损伤。

其他說明

作为 3 种主要表型出现:1-1 型、2-1 型、2-2 型。

免責聲明

仅供研究使用。在法国,在用于科研目的时(包括进口和出口活动(《公共健康法》第L 1211-1条,第2节))该产品为管制品。购买者(即最终用户)需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

R Sanchez et al.
International journal of andrology, 14(6), 423-430 (1991-12-01)
The fusion rate of human sperm with zona-free hamster ova was investigated after induction of the acrosome reaction by exposure to a low temperature (4 degrees C). Sperm were collected from 14 patients, and selected by the 'swim-up' method. The
Eiko Shimada et al.
Transfusion, 47(12), 2315-2321 (2007-09-04)
Congenital haptoglobin deficiency is a risk factor for anaphylactic nonhemolytic transfusion reactions in Japan. The deleted allele of the haptoglobin gene, Hp(del), which causes congenital haptoglobin deficiency, has also been observed in other Northeast Asian populations, such as Korean and
Alexey Tarasov et al.
Biosensors & bioelectronics, 79, 669-678 (2016-01-15)
Quantitative point-of-care (POC) devices are the next generation for serological disease diagnosis. Whilst pathogen serology is typically performed by centralized laboratories using Enzyme-Linked ImmunoSorbent Assay (ELISA), faster on-site diagnosis would infer improved disease management and treatment decisions. Using the model
I B Ross et al.
Journal of neurotrauma, 8(4), 229-238 (1991-01-01)
Previously in our laboratory, nimodipine was effective in reversing posttraumatic ischemia and promoting electrophysiologic recovery in a rat spinal cord injury (SCI) model. However, these beneficial effects were achieved when nimodipine was combined with adjuvant therapy to reverse posttraumatic hypotension
Naoko Osada et al.
The Journal of biological chemistry, 298(9), 102400-102400 (2022-08-22)
The N-glycans attached to proteins contain various GlcNAc branches, the aberrant formation of which correlates with various diseases. N-Acetylglucosaminyltransferase-IVa (GnT-IVa or MGAT4A) and Gnt-IVb (or MGAT4B) are isoenzymes that catalyze the formation of the β1,4-GlcNAc branch in N-glycans. However, the

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務