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Merck
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文件

P0883

Sigma-Aldrich

聚(脱氧腺苷-胸苷)酸 钠盐

double-stranded alternating copolymer

同義詞:

Poly(dA-dT) • Poly(dA-dT)

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About This Item

CAS號碼:
86828-69-5
MDL號碼:
MFCD00131964
分類程式碼代碼:
41106305
NACRES:
NA.51

形狀

powder

儲存溫度

−20°C

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應用

聚(脱氧腺苷-胸苷)（Poly(dA-dT) • Poly(dA-dT)）酸是用于DNA结构动力学和药物相互作用的构象研究的双链交替共聚物DNA模型。

其他說明

双链交替共聚物。

單位定義

一个酶活性单位是指在pH 7.0（1cm光程）条件下，在1.0 ml 20 mM磷酸钠/100 mM NaCl中产生1.0的A260 所需的酶量。

數量

1 mg相当于 ≥12 A260 单位。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

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Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 25(1), 77-84 (2007-08-07)
The thermal denaturation of the synthetic high molecular weight double stranded polynucleotide poly(dA-dT) x poly(dA-dT) has been studied in aqueous buffered solution (Tris 1.0 mM; pH 7.8+/-0.2) in the presence of increasing concentrations of either Ni(2+) (borderline cation) or Cd(2+)
Marta Airoldi et al.
Chirality, 20(9), 951-960 (2008-02-05)
The thermal behavior of the synthetic, high molecular weight, double stranded polynucleotides poly(dA-dT).poly(dA-dT) [polyAT] and poly(dG-dC).poly(dG-dC) [polyGC] solubilized in the aqueous core of the quaternary water-in-oil cationic microemulsion CTAB|n-pentanol|n-hexane|water in the presence of increasing amounts of NiCl(2) at several constant
Jung Hwan Bae et al.
Cells, 8(4) (2019-04-11)
Mitochondrial dysfunction has been implicated in the pathogenesis of insulin resistance and type 2 diabetes. Damaged mitochondria DNA (mtDNA) may have a role in regulating hyperglycemia during type 2 diabetes. Circulating cell-free mitochondria DNA (ccf-mtDNA) was found in serum and
M Vorlícková et al.
Journal of biomolecular structure & dynamics, 3(1), 67-83 (1985-08-01)
The article reviews data indicating that poly(dA-dT).poly(dA-dT) is able of adopting three distinct double helical structures in solution, of which only the A form conforms to classical notions. The other two structures have dinucleotides as double helical repeats. At low
Creina Slator et al.
ACS chemical biology, 11(1), 159-171 (2015-10-22)
The in cellulo catalytic production of reactive oxygen species (ROS) by copper(II) and iron(II) complexes is now recognized as a major mechanistic model in the design of effective cytotoxins of human cancer. The developmental complex, [Cu(o-phthalate)(1,10-phenanthroline)] (Cu-Ph), was recently reported
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