推薦產品
![聚[d（I-C）] lyophilized, pkg of 10 U (10108812001 [A<sub>260</sub> units]), pkg of 50 U (11219847001 [A<sub>260</sub> units])](/deepweb/assets/sigmaaldrich/product/images/352/091/ef743cea-ccd8-44f1-8f3b-dec5a1e4f5d1/640/ef743cea-ccd8-44f1-8f3b-dec5a1e4f5d1.jpg)
應用
聚（脱氧肌苷 - 脱氧胞苷）酸钠盐已用于p65蛋白和neuro-2A蛋白裂解物的电泳迁移位移试验。它还被用作蛋白精氨酸甲基转移酶1（PRMT1）和DNA甲基转移酶1（DNMT1）选择性测定中的底物。
聚（脱氧肌苷 - 脱氧胞苷）酸钠盐已用于合成和表征双（2-（嘧啶-2-γl）乙氧基）烷烃及其药理活性的研究中。聚（脱氧肌苷 - 脱氧胞苷）酸钠盐也已用于研究碳酸钙薄膜在LB/LbL基质上生长。
聚（脱氧肌苷-脱氧胞苷）酸（聚（dI-dC）•聚（dI-dC））是可用作DNA底物的交替共聚物，其可用于评估DNA甲基转移酶（如DNA甲基转移酶1），以及作为双链DNA模型用于DNA结构动力学和药物、小分子、相互作用的构象研究。
生化／生理作用
聚（2′-脱氧肌苷-2′-脱氧胞苷酸），聚（dI-dC）是一种合成的DNA底物。在高盐下，Poly（dI-dC）以左旋螺旋构象存在，并在降低盐浓度过程中恢复为右旋形式。它可用于电泳迁移位移试验（EMSA）。
其他說明
双链交替共聚物
單位定義
在20mM磷酸钠/100mMNaCl(pH 7.0)缓冲液中，一个单位可在1.0ml中产生A260 = 1.0（1cm光程）
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays
Ye F, et al.
Journal of Chemical Information and Modeling, 58(5), 1066-1073 (2018)
Dimitrios Priftis et al.
Langmuir : the ACS journal of surfaces and colloids, 28(23), 8721-8729 (2012-05-15)
A systematic study of the interfacial energy (γ) of polypeptide complex coacervates in aqueous solution was performed using a surface forces apparatus (SFA). Poly(L-lysine hydrochloride) (PLys) and poly(L-glutamic acid sodium salt) (PGA) were investigated as a model pair of oppositely
Chao Bi et al.
Plant molecular biology, 94(1-2), 197-213 (2017-04-10)
It has been known that ABA INSENSITIVE 5 (ABI5) plays a vital role in regulating seed germination. In the present study, we showed that inhibition of the catalase activity with 3-amino-1,2,4-triazole (3-AT) inhibits seed germination of Col-0, abi5 mutants and
Ligang Fan et al.
Nature communications, 11(1), 4947-4947 (2020-10-04)
Pseudomonas syringae is a Gram-negative and model pathogenic bacterium that causes plant diseases worldwide. Here, we set out to identify binding motifs for all 301 annotated transcription factors (TFs) of P. syringae using HT-SELEX. We successfully identify binding motifs for
Meaghan L Clark et al.
Inorganic chemistry, 47(20), 9410-9418 (2008-09-25)
This paper focuses on DNA-binding interactions exhibited by Pt(dma-T)CN(+), where dma-T denotes 4'-dimethylamino-2,2':6',2''-terpyridine, and includes complementary studies of the corresponding pyrr-T complex, where pyrr-T denotes 4'-(N-pyrrolidinyl)-2,2':6',2''-terpyridine. The chromophores are useful for understanding the interesting and rather intricate DNA-binding interactions exhibited
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務