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Merck
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文件

N7382

Sigma-Aldrich

亚硝基吗啉

同義詞:

NMOR

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About This Item

經驗公式(希爾表示法):
C4H8N2O2
CAS號碼:
分子量::
116.12
MDL號碼:
分類程式碼代碼:
41116105
PubChem物質ID:
NACRES:
NA.25

形狀

solid

SMILES 字串

O=NN1CCOCC1

InChI

1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2

InChI 密鑰

ZKXDGKXYMTYWTB-UHFFFAOYSA-N

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生化/生理作用

Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.

包裝

散装

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Carc. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析證明 (COA)

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W Lijinsky et al.
Carcinogenesis, 3(8), 911-915 (1982-01-01)
A comparison was made of the carcinogenic effectiveness of some cyclic nitrosamines containing oxygen in the ring. The compounds were administered to F344 rats at approximately equimolar concentrations in drinking water. Nitrosomorpholine, nitroso-1,3-oxazolidine and nitrosotetrahydro-1,3-oxazine were of similar potency and
Jutta Groos et al.
Mathematical biosciences, 202(2), 248-268 (2006-04-11)
Several hypotheses are established to describe the formation and progression of foci of altered hepatocytes (FAH). A common model of hepatocarcinogenesis is the mutation model (MM), which is based on the assumption that cells have to undergo multiple successive changes
Yong-Cang Wang et al.
Hepato-gastroenterology, 58(112), 2032-2035 (2012-01-12)
Concern that much controversy exists with respect to the role of estrogen in hepatocarcinogenesis prompted us to examine the effect of estrogen, at physiological concentrations, on our established HCC rat model induced by diethylnitrosamine and N-nitrosomorpholine. Female Sprague-Dawley rats were
D Slamenova et al.
Neoplasma, 55(4), 280-285 (2008-05-29)
N-nitrosomorpholine (NMOR) belongs to the group of N-nitrosamines and represents a known hepatocarcinogen. Exposure to this compound is considered to be a potential health hazard to humans. There is, however, considerable evidence that the effect of many carcinogenic agents can
Olga Teufelhofer et al.
Electrophoresis, 27(20), 4112-4120 (2006-10-21)
Comparative proteome data of normal and diseased tissue samples are difficult to interpret. Proteins detected in tissues are derived from different cell types and blood constituents. Pathologic or toxicant-induced aberrations may affect the proteome profile of tissues in several ways

文章

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

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