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N5254

Sigma-Aldrich

Neuraminidase Agarose from Clostridium perfringens (C. welchii)

Type VI-A, ammonium sulfate suspension

同義詞:

受体破坏酶, 唾液酸酶

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About This Item

酶委員會編號:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

種類

Type VI-A

形狀

ammonium sulfate suspension

比活性

20-60 units/g agarose

標籤範圍

0.6-1.8 units per mL gel
20-60 units per g agarose

基質

beaded agarose

儲存溫度

2-8°C

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相關類別

一般說明

Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.

應用

Agarose-linked neuraminidase from Clostridium perfringens can be used for the detection of total and desialylated sex hormone-binding globulin in human serum samples.
Neuraminidase from Clostridium perfringens has been used in a study to assess a genetic polymorphism of human serum glycoprotein (inter-α-trypsin-inhibitor). It has also been used in a study to investigate the inhibition of neuraminidase by chemically sulphated glycopeptides.

單位定義

One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37 °C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate.

外觀

Suspension in 2.0 M (NH4)2SO4 solution, pH 7.0.

準備報告

Prepared from Neuraminidase, Type VI (N 3001).

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46
Arnon, T.I., et al
Immunobiol., 103(2), 664-672 (2004)
N Mian et al.
The Biochemical journal, 181(2), 377-385 (1979-08-01)
Chemically sulphated glycopeptides (derived from pig duodenal mucosa) inhibited Clostridium perfringens neuraminidase (EC 3.2.1.18) activity in a pH-dependent manner. Analysis of inhibition kinetics data indicated that, although the enzyme inhibition could not be categorized into any of the classical types
T I Arnon et al.
European journal of immunology, 31(9), 2680-2689 (2001-09-06)
Natural killer (NK) cells destroy virus-infected and tumor cells without prior antigen stimulation. The NK cell cytotoxicity is regulated in large part by the expression of NK cell receptors that are able to bind major histocompatibility complex (MHC) class I
Measurements of total and desialylated sex hormone binding globulin in serum by ELISA.
J Vaysse et al.
Clinical chemistry, 44(4), 882-884 (1998-04-29)
U Vogt et al.
Human genetics, 84(2), 151-154 (1990-01-01)
A new genetic polymorphism of a human serum glycoprotein, the inter-alpha-trypsin-inhibitor (ITI), has been demonstrated by population and family studies. Sera were examined after neuraminidase treatment by isoelectric focusing on agarose gels followed by immunoblotting or by immunofixation with specific

文章

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

瞭解半乳醯胺酸的結構、功能、訊號傳遞及變性。輕鬆尋找研究ialic acid 的產品。

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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