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重要文件

J3580

Sigma-Aldrich

JNJ 17203212

≥98% (HPLC)

同義詞:

N1-(3-Trifluoromethylpyrid-2-yl)-N4-(4-trifluoromethylpyrid-2-yl)carbamoylpiperazine

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About This Item

經驗公式(希爾表示法):
C17H15F6N5O
CAS號碼:
分子量::
419.32
分類程式碼代碼:
12352200
暫時無法取得訂價和供貨情況

化驗

≥98% (HPLC)

形狀

powder

顏色

white to off-white

溶解度

DMSO: >20 mg/mL

起源

Johnson & Johnson

儲存溫度

−20°C

SMILES 字串

FC(F)(F)c1c(nccc1)N2CCN(CC2)C(=O)Nc3ncc(cc3)C(F)(F)F

InChI

1S/C17H15F6N5O/c18-16(19,20)11-3-4-13(25-10-11)26-15(29)28-8-6-27(7-9-28)14-12(17(21,22)23)2-1-5-24-14/h1-5,10H,6-9H2,(H,25,26,29)

InChI 密鑰

JFRYYGVYCWYIDQ-UHFFFAOYSA-N

生化/生理作用

JNJ 17203212 is a reversible, competitive and potent TRPV1 antagonist that does not inhibit related TRP channels such as TRPV2, TRPV4, or TRPA1. Listed in BJP with IC50= 65 nM. TRPV1 channels are activated by heat, capsaicin and the endocannabinoid anandamide. Interest in TRPV1 antagonists in the transmission and modulation of pain.
JNJ 17203212 is a reversible, competitive and potent TRPV1 antagonist.

特點和優勢

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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