推薦產品
化驗
≥98% (HPLC)
形狀
powder
光學活性
[α]/D -80 to -99°, c = 0.5 in chloroform-d
儲存條件
desiccated
protect from light
顏色
orange-brown
溶解度
DMSO: ≥5 mg/mL
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
C[C@H]1COC2=C1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23
InChI
1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
InChI 密鑰
GVKKJJOMQCNPGB-JTQLQIEISA-N
生化／生理作用
隐丹参酮是一种从亚洲药用植物丹参的根中分离出的醌类二萜。最新研究表明，该化合物是有效的 STAT3 抑制剂。隐丹参酮通过 JAK2 非依赖性机制快速抑制 STAT3 Tyr705 磷酸化。隐丹参酮通过与单体 STAT3 结合选择性抑制 STAT3 活化的细胞系，随后阻断二聚化并抑制 STAT3 转录调节活性。以前，研究据报道了该化合物通过抑制环加氧酶 II 活性和内皮素-1 的表达来消除炎症。丹参（Danshen）的干根在传统的东方医学中通常用于治疗循环障碍、肝病、冠心病、肝炎和慢性肾衰竭。
隐丹参酮是一种特异性 STAT3 抑制剂。它可以防止 STAT3 二聚化。
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
從最近期的版本中選擇一個：
分析證明 (COA)
Lot/Batch Number
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