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B7260

Sigma-Aldrich

Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride

protease substrate, ≥99% (TLC), powder

同義詞:

Bz-Arg-AMC hydrochloride

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About This Item

經驗公式（希爾表示法）:
C23H25N5O4 · HCl
CAS號碼:
83701-04-6
分子量：:
471.94
MDL號碼:
MFCD00039020
分類程式碼代碼:
12352204
PubChem物質ID:
24891979
NACRES:
NA.83
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產品名稱

Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride, protease substrate

化驗

≥99% (TLC)

形狀

powder

溶解度

DMSO:methanol (1:1): 20 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@H](CCCNC(N)=N)NC(=O)c3ccccc3)ccc12

InChI

1S/C23H25N5O4.ClH/c1-14-12-20(29)32-19-13-16(9-10-17(14)19)27-22(31)18(8-5-11-26-23(24)25)28-21(30)15-6-3-2-4-7-15;/h2-4,6-7,9-10,12-13,18H,5,8,11H2,1H3,(H,27,31)(H,28,30)(H4,24,25,26);1H/t18-;/m0./s1

InChI 密鑰

XKAVYOJOHZLTDF-FERBBOLQSA-N

應用

Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride has been used:
  • as a substrate for trypsin-like proteolysis of peptide in red blood cells[1]
  • as a substrate for midgut proteases of Pieris brassicae[2]
  • as a substrate in screening serine protease activity of venom[3]

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

基底

A sensitive fluorogenic substrate for papain and trypsin.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

Lot/Batch Number
BCCJ5437
BCCF4906
BCBP5436V
BCBG5111V
BCBD2059V

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Trypsin-like proteolytic contamination of commercially available psa purified from human seminal fluid
Manning ML, et al.
Prostate, 72(11), 1233-1238 (2012)
Purification and functional characterisation of rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros
Vaiyapuri S, et al.
Testing, 5(3), e9687-e9687 (2010)
Carmen Navarro-Guillén et al.
PloS one, 16(4), e0248356-e0248356 (2021-04-10)
New and more efficient methods to sustainably intensify Aquaculture production are essential to attain the seafood demand for direct human consumption in the near future. Nutrition has been identified as one strategy of early exposure that might affect animal early
Kanaoka, Y., et al.
Chemical & Pharmaceutical Bulletin, 25, 3126-3126 (1977)
Rakesh Kumar et al.
Frontiers in physiology, 6, 95-95 (2015-04-16)
Pieris brassicae L. is a serious pest of cultivated crucifers in several parts of the world. Larvae of P. brassicae also feed prolifically on garden nasturtium (Tropaeolum majus L., of the family Tropaeolaceae). Proteolytic digestion was studied in larvae feeding
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