62316

脂肪酶 来源于皱褶假丝酵母

powder, yellow-brown, ≥2 U/mg

• 同義詞: CCL
• CAS號碼: 9001-62-1
• 酶委員會編號: 3.1.1.3 (BRENDA, IUBMB)
• EC號碼: 232-619-9
• MDL號碼: MFCD00131509
• 分類程式碼代碼: 12352204
• NACRES: NA.54

屬性

• 生物源: fungus (Candida rugosa)
• 品質等級: 100
• 形狀: powder
• 比活性: ≥2 U/mg
• 分子量: M_r ~67000
• 儲存條件: dry at room temperature
• 濃度: ≤100%
• 技術: analytical sample preparation: suitable
• 顏色: yellow-brown
• pH值範圍: 6.5—7.5 (0.01 g/L)
• 溶解度: water: slightly soluble
• 應用: sample preservation
• 儲存溫度: 2-8°C
• InChI: 1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;
• InChI 密鑰: QWZUIMCIEOCSJF-CHHCPSLASA-N
• 基因資訊: fungus ... LAP1(2544)

描述

一般說明

Research Area: Cell Signaling
The lipase enzyme is a naturally occurring enzyme present in both the stomach and pancreatic juice. It is expressed and active in various tissues. For instance, hepatic lipases are found in the liver, hormone-sensitive lipases in adipocytes, lipoprotein lipase on the vascular endothelial surface, and pancreatic lipase in the small intestine. These lipases are classified within the alpha/beta-hydrolase fold superfamily of enzymes.

應用

Lipase from Candida rugosa has been used to study and evaluate its effect on the anatomical structure and chemical composition of archaeological wood samples. It has also been used to remove the oily dirt from a child′s tunic dated to the Coptic period and also to study the effect of the enzymatic treatment on the mechanical and optical parameters of linen using scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), CIE-Lab values and ASTM method D5035.

生化／生理作用

Lipases, as a group of enzymes, are responsible for breaking down triglycerides into free fatty acids and glycerol, playing a pivotal role in the digestion, hydrolysis, and absorption of fat-soluble vitamins in pancreatic secretions. It contributes to the maintenance of proper gallbladder function. These enzymes, derived from animals, plants, and various microorganisms, are known for their stability and are often described as nature′s catalysts. While microbial lipases are the primary choice for commercial applications, they possess the unique ability to hydrolyze fats into fatty acids and glycerols at the water-lipid interface and can also reverse this reaction in non-aqueous environments. Elevated serum lipase levels can indicate pancreatitis. Understanding the role of lipase is essential for the pathophysiology of fat necrosis and acute and chronic pancreatitis. Lipases are also involved in the mechanism of some cholesterol-lowering medications.

已知皱纹念珠菌脂肪酶可催化水解反应，尤其是蓖麻油酸的产生。

單位定義

1U对应于在pH 8.0和40℃下每分钟释放1 μmol油酸的酶量（三油精作为底物，目录号62314）

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H334
• 防範說明: P261 - P284 - P501
• 危險分類: Resp. Sens. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)