PHR1606

醋酸氢化可的松

Pharmaceutical Secondary Standard; Certified Reference Material

• 同義詞: 11β,17α,21-三羟基-4-孕烯-3,20-二酮 21-乙酸酯, 17-α-羟基皮质甾酮乙酸酯, 17-羟基皮质甾酮 21-乙酸酯, 21-乙酰氧基-4-孕烯-11β,17α-二醇-3,20-二酮, 4-孕烯-11β,17α,21-三醇-3,20-二酮 21-乙酸酯
• 經驗公式（希爾表示法）: C₂₃H₃₂O₆
• CAS號碼: 50-03-3
• 分子量：: 404.50
• Beilstein: 2066841
• EC號碼: 200-004-4
• MDL號碼: MFCD00037714
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823503
• NACRES: NA.24

屬性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 584; traceable to Ph. Eur. H1400000; traceable to USP 1317007
• API 家族: hydrocortisone
• CofA: current certificate can be downloaded
• 包裝: pkg of 1 g
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• mp: 223 °C (dec.) (lit.)
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
• InChI 密鑰: ALEXXDVDDISNDU-JZYPGELDSA-N
• 基因資訊: human ... NR3C1(2908)

描述

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Hydrocortisone Acetate belongs to the class of corticosteroids, exhibiting antipruritic, anti-inflammatory and vasoconstrictive properties.[1] It is used in the treatment of various conditions such as allergic and breathing disorders or skin conditions.[2]

應用

Hydrocortisone Acetate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography and thin layer chromatography techniques.[1][2]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC3177 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360Df,H373
• 防範說明: P202 - P260 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 1B - STOT RE 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable