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重要文件

L4509

Sigma-Aldrich

十二烷基硫酸钠

Sodium dodecyl sulfate

ReagentPlus®, ≥98.5% (GC)

同義詞:

SDS, 十二烷基硫酸盐 钠盐, 十二烷基硫酸钠, 月桂基硫酸盐 钠盐, 月桂基硫酸钠

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About This Item

線性公式:
CH3(CH2)11OSO3Na
CAS號碼:
分子量::
288.38
Beilstein:
3599286
EC號碼:
MDL號碼:
分類程式碼代碼:
12161900
eCl@ss:
39093306
PubChem物質ID:
NACRES:
NA.21
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生物源

synthetic

品質等級

描述

anionic

產品線

ReagentPlus®

化驗

≥98.5% (GC)

形狀

powder

分子量

micellar avg mol wt 18,000

凝集数

62

雜質

<2.0% water (Karl Fischer)

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

轉變溫度

cloud point >100 °C

溶解度

water: soluble

密度

0.425 g/cm3

正離子痕跡

Na: 7.0-9.0%

HLB

40

SMILES 字串

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI 密鑰

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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一般說明

十二烷基硫酸钠(SDS)也称月桂酸硫酸钠,是一种广为人知的阴离子表面活性剂,属于有机化合物中的有机硫酸酯类。作为去污剂它在离子和阴离子条件下均有去污功效。作为蛋白质变性剂SDS起着重要作用,在蛋白质提取和SDS-PAGE等操作中促进蛋白质的增溶和变性。它在蛋白质和脂质的电泳分离中起重要作用,是各种生物学实验中测定这些分子不可缺少的工具。总之,在生物化学和细胞生物学研究领域,十二烷基硫酸钠是探索生物分子必不可少的工具。

應用

十二烷基硫酸钠(SDS)已用于:
  • 基于选择性化合物的敏感性进行的肠杆菌科菌株鉴定[1]
  • 对人体皮肤的体外体内处理,以评估27-kDa热激蛋白(HSP27)在潜在皮肤刺激方面的核定位作用[2]
  • 猪心脏瓣膜组织脱细胞[3]
  • 处理精子以体外诱导精子解聚[4]

阴离子洗涤剂

生化/生理作用

十二烷基硫酸钠(SDS)有助于快速破坏生物膜。它通常用作纯化核酸的几种试剂的主要成分之一。SDS可以阻断RNase和脱氧核糖核酸酶(DNase)活性。[5]

特點和優勢

  • 适用于细胞生物学和生物化学研究
  • 适用于多种研究应用的优质化学制品

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

4.1B - Flammable solid hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

338.0 °F

閃點(°C)

170 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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存取文件庫

Utility of light scatter in the morphological analysis of sperm
Zucker RM, et al.
Cytometry, 39-47 (1992)
A rapid and reliable alternative to ISO 21528-1: 2004 for detection of Enterobacteriaceae
Joosten H, et al.
International Journal of Food Microbiology, 125(3), 344-346 (2008)
Resilient ribonucleases
RNA Methodologies: A Laboratory Guide for Isolation and Characterization, 32-45 (1993)
Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C
Boxman ILA, et al.
Experimental Dermatology, 11(6), 509-517 (2002)
Sub-Micellar Concentration of Sodium Dodecyl Sulphate Prevents Thermal Denaturation Induced Aggregation of Plant Lectin, Jacalin
Lavanya V, et al
The Protein Journal, 36(1), 17-27 (2017)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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