Exosomes are extracellular vesicles (EVs) of ~20-200 nm diameter that shuttle DNAs, RNAs, proteins and other biomolecules between cells. The large number of biomolecules present in exosomes demands the frequent use of high-throughput analysis. This, in turn, requires technical replicates
Effect of an experimental proteasome inhibitor on the cytoskeleton, cytosolic protein turnover, and induction in the neuronal cells in vitro.
Csizmadia V, et al.
Neurotoxicology, 29, 232-232 (2008)
Emerin suppresses Notch signaling by restricting the Notch intracellular domain to the nuclear membrane.
Biochimica et Biophysica Acta, 1864, 303-303 (2017)
Ahmed H
Principles and Reactions of Protein Extraction, Purification, and Characterization (2004)
Frontiers in cellular neuroscience, 12, 433-433 (2018-12-14)
Addressing potential sex differences in pre-clinical studies is crucial for developing therapeutic interventions. Although sex differences have been reported in epidemiological studies and from clinical experience, most pre-clinical studies of neuroinflammation use male rodents; however, sexual dimorphisms in microglia might