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Merck
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文件

A3035

Sigma-Aldrich

对乙酰氨基酚

analytical standard

同義詞:

4′-羟基乙酰苯胺, 4-乙酰氨基酚, N-(4-羟基苯基)乙酰胺, N-乙酰基-4-氨基苯酚, APAP, 扑热息痛

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About This Item

線性公式:
CH3CONHC6H4OH
CAS號碼:
103-90-2
分子量：:
151.16
Beilstein:
2208089
EC號碼:
203-157-5
MDL號碼:
MFCD00002328
分類程式碼代碼:
41116107
PubChem物質ID:
24890717
NACRES:
NA.21

等級

analytical standard

品質等級

300

形狀

powder

包裝

vial of 1 g

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

168-172 °C (lit.)

應用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

SMILES 字串

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI 密鑰

RZVAJINKPMORJF-UHFFFAOYSA-N

基因資訊

human ... FAAH(2166) , PTGS1(5742) , PTGS2(5743) , TRPV1(7442)

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相關類別

應用

镇痛剂。

包裝

棕色螺纹盖样品瓶包装

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

364.3 °F - Pensky-Martens closed cup

閃點（°C）

184.6 °C - Pensky-Martens closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

分析證明 (COA)

Lot/Batch Number
0000373099
0000373100
0000366464
0000321410
0000373100

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Karel Allegaert et al.
Archives of disease in childhood, 98(6), 462-466 (2013-04-23)
There remains a need for alternative medical treatments for patent ductus arteriosus (PDA) closure in extreme preterm neonates because of therapeutic failure and adverse effects associated with non-selective cyclo-oxygenase inhibitors. Reports of an association between paracetamol exposure and PDA closure
Garry G Graham et al.
Drug safety, 28(3), 227-240 (2005-03-01)
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
Garry G Graham et al.
Inflammopharmacology, 21(3), 201-232 (2013-05-31)
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective
Edward Munsterhjelm et al.
Anesthesiology, 103(4), 712-717 (2005-09-30)
Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet
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