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Merck
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重要文件

540223

Sigma-Aldrich

Purmorphamine

≥98% (HPLC), liquid, Hedgehog signaling activator, Calbiochem

同義詞:

InSolution Purmorphamine

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About This Item

分類程式碼代碼:
12352116
NACRES:
NA.77
暫時無法取得訂價和供貨情況

產品名稱

Purmorphamine, InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells

品質等級

化驗

≥98% (HPLC)

形狀

liquid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated (hygroscopic)
protect from light

儲存溫度

−20°C

一般說明

A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.

應用

InSolution Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

外觀

A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.

重構

Following initial thaw, aliquot and freeze (-20°C).

其他說明

Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazard

訊號詞

Warning

危險聲明

危險分類

Muta. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

188.6 °F - closed cup

閃點(°C)

87 °C - closed cup


分析證明 (COA)

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    1. This product is not sterile.

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