434625

Leukotriene B₄

≥97% (HPLC), oil, proinflammatory agent, Calbiochem^®

• 同義詞: Leukotriene B₄, LTB₄, 5(S),12(R)-Dihydroxy-6- cis-8- trans-10- trans-14- cis-eicosatetraenoic Acid
• 經驗公式（希爾表示法）: C₂₀H₃₂O₄
• CAS號碼: 71160-24-2
• 分子量：: 336.47
• MDL號碼: MFCD00135630
• 分類程式碼代碼: 12352211
• NACRES: NA.77

屬性

• 產品名稱: Leukotriene B₄, Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium.
• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: oil
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: clear
• 溶解度: ethanol: soluble
• 運輸包裝: wet ice
• 儲存溫度: −70°C
• SMILES 字串: OC(CCCC(=O)O)\C=C\C=C\C=C\C(O)C\C=C\CCCCC
• InChI: 1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6+,14-10+,15-11+
• InChI 密鑰: VNYSSYRCGWBHLG-XUOUMLBJSA-N

描述

一般說明

Potent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.

Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.

生化／生理作用

Cell permeable: no

Primary Target
Polymorphonuclear leukocytes

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Flammable (J)

外觀

In Ethanol.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Kendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem.266, 24763.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H319
• 防範說明: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Flam. Liq. 2
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2