137141

精胺 四盐酸盐

EMPROVE^® EVOLVE

• 同義詞: N,N′-双(3-氨丙基)-1,4-丁二胺 四盐酸盐
• 經驗公式（希爾表示法）: C₁₀H₂₆N₄ · 4HCl
• CAS號碼: 306-67-2
• 分子量：: 348.18
• Beilstein: 3911771
• MDL號碼: MFCD00012914
• 分類程式碼代碼: 12352116

屬性

• 生物源: synthetic
• 品質等級: 400
• agency: non-compendial
• 形狀: powder
• 濃度: 99.0-101.0 % (w/w) (T)
• 雜質: ≤5000 mg/kg ethanol (HS-GC); ≤890 mg/kg toluene (HS-GC)
• mp: 310-311 °C (dec.) (lit.)
• 正離子痕跡: Al: ≤25 mg/kg; Cr: ≤2.5 mg/kg; Cu: ≤25 mg/kg; Fe: ≤130 mg/kg; Ni: ≤2.5 mg/kg; Zn: ≤130 mg/kg
• 適合性: corresponds for identity (¹H-NMR)
• 應用: pharma/biopharma processes
• SMILES 字串: Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
• InChI: 1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
• InChI 密鑰: XLDKUDAXZWHPFH-UHFFFAOYSA-N

描述

一般說明

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

應用

用于从低盐缓冲液中沉淀 DNA。

生化／生理作用

多胺位点混合型 NMDA 激动-拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。

多胺位点混合型 NMDA 激动-拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315 - H319
• 防範說明: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable