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D3511

Sigma-Aldrich

反式-4,5-二羟基-1,2-二噻烷

greener alternative

≥99%

同義詞:

反式-1,2-二噻烷-4,5-二醇, 氧化 DTT

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About This Item

經驗公式(希爾表示法):
C4H8O2S2
CAS號碼:
分子量::
152.24
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
暫時無法取得訂價和供貨情況

品質等級

化驗

≥99%

形狀

powder

環保替代產品評分

old score: 9
new score: 6
Find out more about DOZN™ Scoring

環保替代產品特色

Atom Economy
Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

130-132 °C (lit.)

環保替代類別

儲存溫度

2-8°C

SMILES 字串

O[C@@H]1CSSC[C@H]1O

InChI

1S/C4H8O2S2/c5-3-1-7-8-2-4(3)6/h3-6H,1-2H2/t3-,4-/m1/s1

InChI 密鑰

YPGMOWHXEQDBBV-QWWZWVQMSA-N

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一般說明

反式 -4,5-二羟基-1,2-二噻烷(氧化 dtt)是二硫苏糖醇的分子内二硫键形式。它是一种强还原剂,能够通过激活应激反应基因引发分子应激反应。[1][2]
我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。该产品属于再设计产品类别,在“原子经济性”、“危险性较小的化学合成”和“使用可再生原料”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

聯結

二硫苏糖醇 (DTT) 的氧化型。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jing Li et al.
PloS one, 12(2), e0172504-e0172504 (2017-02-23)
Starch breakdown in leaves at night is tightly matched to the duration of the dark period, but the mechanism by which this regulation is achieved is unknown. In Arabidopsis chloroplasts, β-amylase BAM3 hydrolyses transitory starch, producing maltose and residual maltotriose.
Reduction of trans-4, 5-Dihydroxy-1, 2-dithiane by Cellular Oxidoreductases Activates gadd153/chop and grp78 Transcription and Induces Cellular Tolerance in Kidney Epithelial Cells.
Halleck MM
The Journal of Biological Chemistry, 272(35), 21760-21766 (1997)
Hélène Launay et al.
Journal of molecular biology, 430(8), 1218-1234 (2018-03-05)
Among intrinsically disordered proteins, conditionally disordered proteins undergo dramatic structural disorder rearrangements upon environmental changes and/or post-translational modifications that directly modulate their function. Quantifying the dynamics of these fluctuating proteins is extremely challenging but paramount to understanding the regulation of
Modulating the endoplasmic reticulum stress response with trans-4, 5-dihydroxy-1, 2-dithiane prevents chemically induced renal injury in vivo.
Asmellash S
Toxicological Sciences, 88(2), 576-584 (2005)
Zimai Li et al.
Antioxidants (Basel, Switzerland), 9(10) (2020-10-18)
Reactive sulfane sulfur, including persulfide and polysulfide, is a type of regular cellular component, playing an antioxidant role. Its function may be organelle-dependent; however, the shortage of probes for detecting organellar reactive sulfane sulfur has hindered further investigation. Herein, we

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