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Merck
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重要文件

927449

Sigma-Aldrich

SDASO-L crosslinker

同義詞:

2,5-Dioxopyrrolidin-1-yl 3-((2-(3-(3-methyl-3H-diazirin-3-yl)propanamido)ethyl)sulfinyl) propanoate, Succinimidyl diazirine sulfoxide

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About This Item

經驗公式(希爾表示法):
C14H20N4O6S
分子量::
372.40
分類程式碼代碼:
12352106
暫時無法取得訂價和供貨情況

形狀

chunks

品質等級

儲存溫度

−20°C

SMILES 字串

C1C(N(C(C1)=O)OC(CC[S](CCN(C(CCC2([C])N=N2)=O)[H])=O)=O)=O

應用

SDASO-L (succinimidyl diazirine sulfoxide, long version) is mass-spectrometry cleavable heterobifunctional cross-linker, which can be used in the analysis of protein structure, or protein-protein interactions. SDASO-L is photoactivated, allowing for the first time photocross-linking of proteins, and rapid, accurate analysis by MS.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

相關產品

象形圖

Flame

訊號詞

Danger

危險聲明

危險分類

Self-react. C

儲存類別代碼

5.2 - Organic peroxides and self-reacting hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Craig Gutierrez et al.
Molecular & cellular proteomics : MCP, 20, 100084-100084 (2021-04-30)
Cross-linking mass spectrometry (XL-MS) is a powerful tool for studying protein-protein interactions and elucidating architectures of protein complexes. While residue-specific XL-MS studies have been very successful, accessibility of interaction regions nontargetable by specific chemistries remain difficult. Photochemistry has shown great

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