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產品名稱
泊马度胺, ≥98% (HPLC)
ligand
pomalidomide
品質等級
化驗
≥98% (HPLC)
形狀
powder
反應適用性
reagent type: ligand
顏色
yellow
溶解度
DMSO: ≥14 mg/mL
儲存溫度
2-8°C
SMILES 字串
Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
InChI
1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)
InChI 密鑰
UVSMNLNDYGZFPF-UHFFFAOYSA-N
基因資訊
human ... CRBN(51185) , CUL4A(8451) , DDB1(1642) , RBX1(9978)
應用
生化／生理作用
泊马度胺是一种有效的胎儿血红蛋白 (HbF) 诱导剂，可使关键的γ-珠蛋白抑制因子、SRY-box 转录因子 6 (SOX6) 和 BAF 染色质重塑复合物亚基 (BCL11A)下调。[3]
泊马度胺是第二代免疫调节剂，TNF-α抑制剂和沙利度胺类似物。
特點和優勢
《受体分类和信号转导》手册的 细胞因子受体（肿瘤坏死受体家族） 页面有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。
相關產品
產品號碼
描述
訂價
訊號詞
Danger
危險聲明
危險分類
Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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分析證明 (COA)
Lot/Batch Number
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