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225916

Sigma-Aldrich

苄基氯化镁 溶液

2.0 M in THF

同義詞:

(Phenylmethyl)magnesium chloride, Benzylchloromagnesium, Chloro(phenylmethyl)magnesium

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About This Item

線性公式:
C6H5CH2MgCl
CAS號碼:
分子量::
150.89
Beilstein:
878506
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22
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品質等級

反應適用性

reaction type: Grignard Reaction

濃度

2.0 M in THF

密度

1.031 g/mL at 25 °C

官能基

phenyl

SMILES 字串

Cl[Mg]Cc1ccccc1

InChI

1S/C7H7.ClH.Mg/c1-7-5-3-2-4-6-7;;/h2-6H,1H2;1H;/q;;+1/p-1

InChI 密鑰

NRAFPLGJPPJUNB-UHFFFAOYSA-M

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一般說明

氯苄镁是一种有机金属化合物,可用作Lewis酸和强碱。[1]

應用

苄基氯化镁(格利雅试剂)可用作烷基化试剂:
  • 烷基化喹啉基功能化Cp−铬(III)复合物,以作为前体用于制备活性烯烃聚合催化剂。[2]
  • 合成2,3-二取代苯并吡喃-4-酮[3]、6-氯代-8- 甲基嘌呤衍生物[4]和苯基丙氨酸衍生物。[5]

訊號詞

Danger

危險分類

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

標靶器官

Central nervous system, Respiratory system

安全危害

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

1.4 °F - closed cup

閃點(°C)

-17 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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A facile three-step synthesis of 1, 2-amino alcohols using the Ellman homochiral tert-butylsulfinamide
Barrow JC, et al.
Tetrahedron Letters, 42(11), 2051-2054 (2001)
Quinolyl-functionalised Cp-chromium polymerisation catalysts: synthesis and crystal structures of alkylation products
Enders M, et al.
Journal of Organometallic Chemistry, 687(1), 125-130 (2003)
A novel synthesis of 2, 3-disubstituted benzopyran-4-ones and application to the solid phase
Harikrishnan LS and Showalter HD H
Tetrahedron, 56(4), 515-519 (2000)
Benzylmagnesium Chloride
Herman G
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Dichotomy in regioselective cross-coupling reactions of 6, 8-dichloropurines with phenylboronic acid and methylmagnesium chloride: synthesis of 6, 8-disubstituted purines
Hocek M, et al.
Synthesis, 2004(06), 889-894 (2004)

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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