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重要文件

189871

Sigma-Aldrich

乙基溴化镁 溶液

3.0 M in diethyl ether

同義詞:

EtMgBr溶液

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About This Item

線性公式:
CH3CH2MgBr
CAS號碼:
分子量::
133.27
Beilstein:
3587203
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22
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形狀

liquid

品質等級

反應適用性

reaction type: Grignard Reaction

濃度

3.0 M in diethyl ether

bp

34.6 °C/1.013  hPa

密度

1.02 g/mL at 25 °C

SMILES 字串

[CC[Mg]Br]
CC[Mg]Br

InChI

[1S/C2H5.BrH.Mg/c1-2;;/h1H2,2H3;1H;/q;;+1/p-1]
1S/C2H5.BrH.Mg/c1-2;;/h1H2,2H3;1H;/q;;+1/p-1

InChI 密鑰

[HSNUIYJWTSJUMS-UHFFFAOYSA-N]
TWTWFMUQSOFTRN-UHFFFAOYSA-M

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一般說明

乙基溴化镁是一种有机镁化合物,俗称格氏试剂。[1]它是一种功能强大的碳亲核试剂,主要用于 C-C 键的形成。[2]

應用

乙基溴化镁溶液(3.0 M,乙醚中)可用于铜 (I) 催化的烯丙基取代反应。[2]

包裝

建议将25 mL Sure/Seal 瓶作为一次性瓶使用。反复穿刺可能会导致产品性能下降。

法律資訊

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1

標靶器官

Respiratory system

安全危害

儲存類別代碼

4.3 - Hazardous materials which set free flammable gases upon contact with water

水污染物質分類(WGK)

WGK 1

閃點(°F)

-40.0 °F - closed cup

閃點(°C)

-40 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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存取文件庫

Enantioselective Copper-Catalyzed SN2? Substitution with Grignard Reagents.
Alexakis A, et al.
Synlett, 0927-0930 (2001)
Organic Chemistry, 542-542 (2008)
T Nishiyama et al.
Chemical & pharmaceutical bulletin, 48(12), 1999-2002 (2001-01-06)
The direct alpha-bromination of various ketones using trifluoromethanesulfonic anhydride and Grignard reagent or magnesium bromide in ether gave the corresponding alpha-bromo ketones in moderate to good yields under mild reaction conditions.
F Turon et al.
Lipids, 37(8), 817-821 (2002-10-10)
An analytical procedure was developed for regiodistribution analysis of TAG using alpha-MAG prepared by an ethyl magnesium bromide deacylation. In the present communication, the deacylation procedure is shown to lead to representative alpha-MAG, allowing the composition of the native TAG
R G Xie et al.
Steroids, 55(11), 488-490 (1990-11-01)
The reaction of ethyl magnesium bromide and 17 alpha-ethynylestradiol with formaldehyde in the presence of triethyl phosphate or hexamethylphosphoramide gave the 2- and 4-formyl-17 alpha-ethynylestradiol in high yield. Treatment of the formyl derivatives with an alkaline solution of hydrogen peroxide

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