![1H-1,2,3-三唑并[4,5-b]吡啶 98%](/deepweb/assets/sigmaaldrich/product/structures/344/744/1e7fa2cf-1258-48e0-909f-92509981f43d/640/1e7fa2cf-1258-48e0-909f-92509981f43d.png)
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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About This Item
推荐产品
方案
98%
表单
powder
旋光性
[α]20/D −126°, c = 1.5 in acetic acid
mp
229-232 °C (lit.)
官能团
ester
hydroxyl
SMILES字符串
C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C\C=C3/[C@H](O)COC3=O)C(=C)CC[C@H]12
InChI
1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1
InChI key
BOJKULTULYSRAS-OTESTREVSA-N
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应用
- 基于穿心莲内酯的 Keap1-Nrf2 通路药物候选物通过严格的化学信息学筛选：本研究确定了潜在的穿心莲内酯衍生物作为针对 Keap1-Nrf2 通路的创新药物候选物，这对于抗氧化防御机制至关重要。这种方法突出了化合物在开发治疗氧化应激相关疾病方面的多功能性，使其成为学术界和生物技术领域化学家和材料科学家的重要研究领域。（Jain 和 Sudandira Doss，2023 年）
- 基于 TMT 的定量蛋白质组学揭示了穿心莲内酯对 LPS 诱导的肝损伤的靶点：这项对穿心莲内酯在肝损伤模型中诱导的蛋白质组学变化的调查，为其治疗机制提供了见解，突出了其作为炎症和肝病治疗的潜力，这与制药和生化领域的研发相关。（Ge 等人，2023 年）
- 通过功能蛋白质组学研究共价作用天然产物的靶点和抗癌机制：本研究评估了穿心莲内酯在抗癌特性方面的作用，对其在分子水平上的相互作用进行了详细分析，这对于从事新型癌症治疗的材料科学家和化学家至关重要。（Zhao 等人，2023 年）
生化/生理作用
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
其他客户在看
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Helpful?
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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Is the andrographolide can be detected by spectrophotometry UV-VIS ???
1 answer-
Due to the presence of pi bonds in the molecular structure, Andrographolide has chromophores. As a result, this compound may be detected by UV-Vis spectrophotometry.
Please see the link below to review a publication that may be helpful:
https://www.pharmahealthsciences.net/pdfs/volume7-issue12019/8.vol7-issue1-2019-MS-15711.pdfHelpful?
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