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product name
N-羟基-7-偶氮苯并三氮唑 溶液, ~0.6 M in DMF
形狀
liquid
反應適用性
reaction type: Addition Reactions
濃度
~0.6 M in DMF
雜質
<1.0% water
折射率
n20/D 1.441
密度
0.978 g/mL at 20 °C
應用
peptide synthesis
SMILES 字串
On1nnc2cccnc12
InChI
1S/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H
InChI 密鑰
FPIRBHDGWMWJEP-UHFFFAOYSA-N
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一般說明
1-羟基-7-氮杂苯并三唑溶液，又称3H-[1,2,3]-三唑并[4,5-b]吡啶-3-醇，是一种苯并三唑类添加剂，常用作氨基酸和肽的偶联试剂。它还被用于最小化对映异构体生成。
應用
1-羟基-7-氮杂苯并三唑溶液被用作手性肽核酸的固相合成试剂。
其他說明
偶联添加剂，用于肽合成中的高效无外消旋偶联； 片段偶联。
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
136.4 °F - closed cup
閃點（°C）
58 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
Júlia García-Pindado et al.
Biopolymers, 109(10), e23112-e23112 (2018-03-13)
While revisiting biologically active natural peptides, the importance of the tryptophan residue became clear. In this article, the incorporation of this amino acid, brominated at different positions of the indole ring, into cyclic peptides was successfully achieved. These products demonstrated
Synthesis of chiral peptide nucleic acids using Fmoc chemistry
Yun W and Jie-Cheng X
Tetrahedron, 57, 8107-8113 (2001)
L.A. Carpino, A. El-Faham
Tetrahedron, 55, 6813-6813 (1999)
Simone Di Micco et al.
Frontiers in chemistry, 8, 628609-628609 (2021-02-02)
The most severe outcome of COVID-19 infection is the development of interstitial pneumonia causing acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS), both responsible for the infected patients' mortality. ALI and ARDS are characterized by a leakage of
Y. Nishiyama et al.
Tetrahedron Letters, 42, 8789-8789 (2001)
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