SML0803

VUF10661

≥98% (HPLC), Chemokine receptor CXCR3 agonist, powder

• Synonim(y): (3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
• Wzór empiryczny (zapis Hilla): C₄₀H₄₄N₄O₄
• Numer CAS: 914291-63-7
• Masa cząsteczkowa: 644.80
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: VUF10661, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: −20°C

Opis

Biochem/physiol Actions

VUF10661 is a potent agonist of the chemokine receptor CXCR3.

VUF10661 is a potent agonist of the chemokine receptor CXCR3. VUF10661 induces receptor internalization, recruitment of ?-arrestins and activates Gi proteins with similar potency to endogenous CXCL ligands.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335,H413
• pcodes: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable