SMB00089

Dehydroabietic acid

≥90% (LC/MS-ELSD)

• Synonim(y): Abieta-8,11,13-trien-18-oic acid, Dehydroabietate
• Wzór empiryczny (zapis Hilla): C₂₀H₂₈O₂
• Numer CAS: 1740-19-8
• Masa cząsteczkowa: 300.44
• NACRES: NA.25
• PubChem Substance ID: 329824767
• UNSPSC Code: 12352205
• EC Number: 217-102-8
• MDL number: MFCD09839012

Właściwości

• assay: ≥90% (LC/MS-ELSD)
• form: solid
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: CC(C)c1ccc2c(CC[C@H]3[C@@](C)(CCC[C@]23C)C(O)=O)c1
• InChI: 1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1
• InChI key: NFWKVWVWBFBAOV-MISYRCLQSA-N

Opis

General description

Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA).

Application

Dehydroabietic acid has been used as a reference standard:

• to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
• to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
• to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

Biochem/physiol Actions

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS09
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301,H410
• Ostrzeżenia: P273 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable