SAB4500455

Anti-CBP antibody produced in rabbit

affinity isolated antibody

• Synonim(y): CREB-binding protein, CREBBP
• Numer MDL: MFCD02262673
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: antigen 265 kDa
• reaktywność gatunkowa: human, rat, mouse
• stężenie: ~1 mg/mL
• metody: ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• numer dostępu NCBI: Q92793
• numer dostępu UniProt: Q92793
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... CREBBP(1387)

Opis

Opis ogólny

Anti-CBP Antibody detects endogenous levels of total CBP protein. CREB binding protein (CBP) is a histone acetyltransferase, which is part of the KAT3 family of histone acetyltransferases. The gene encoding it is localized on human chromosome 16p13.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human CBP.

Immunogen Range: 1501-1550

Działania biochem./fizjol.

CREB binding protein (CBP) has a role in the activation of the innate immune response, activation of histones and non-histones through acetylation. It also plays an important role in cAMP-dependent and Wnt signaling. The protein is also involved in modulating the cell cycle, DNA damage repair, ubiquitination and antigen presentation. Mutations in the CBP gene have been associated with Rubinstein-Taybi syndrome. It has also been linked with acute lymphoblastic leukemia.

Cechy i korzyści

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Postać fizyczna

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable