RAB0286

Human IL-2 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• Synonim(y): IL-1 beta, Interleukin-1 beta
• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... IL2(3558)
• Input: sample type serum; sample type cell culture supernatant(s); sample type urine; sample type plasma
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Właściwości

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, capture ELISA: suitable
• input: sample type serum; sample type cell culture supernatant(s); sample type urine; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 4 pg/mL; standard curve range: 2.07-1500 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... IL2(3558)

Opis

General description

The Human IL-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-2 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human IL-2

Application

Human IL-2 ELISA Kit has been used in the analysis of interleukins levels in human plasma.[1]

Biochem/physiol Actions

IL-2 (interleukin 2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.[2] It is a type I cytokine.[3] IL-2/IL-2R (interleukin 2/IL-2 receptor) signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK (natural killer) cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.[2][4] It is associated with recurrent oral ulcer, asthma and Mycoplasma pneumoniae infection in children.[5][6] Absence of IL2 in mice causes fatal lymphoproliferative inflammatory disease (IL-2 deficiency syndrome).[7] IL-2 signaling involves three pathways: phosphoinositol 3-kinase (PI3-K)/AKT, Ras-MAPK (mitogen activated protein kinase), and JAK-STAT (Janus kinase - signal transducers and activators of transcription) pathways.[3]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Klasa składowania: 10 - Combustible liquids