K1757

Keratinocyte Growth Factor human

≥95% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, powder, suitable for cell culture

• Synonim(y): hFGF-7, hKGF, FGF-7, KGF
• Numer CAS: 148348-15-6
• UNSPSC Code: 12352202
• NACRES: NA.77
• MDL number: MFCD00212245
• Biological source: human
• Recombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE and HPLC)
• Form: powder
• Mol wt: 18.9 kDa
• Impurities: 1 EU/μg

Właściwości

• Nazwa produktu: Keratinocyte Growth Factor human, KGF, recombinant, expressed in E. coli, powder, suitable for cell culture
• biological source: human
• Quality Segment: 200
• recombinant: expressed in E. coli
• assay: ≥95% (SDS-PAGE and HPLC)
• form: powder
• potency: 0.1-15 ng/mL ED₅₀/EC₅₀
• quality: endotoxin tested
• mol wt: 18.9 kDa
• packaging: pkg of 10 and 50 μg
• technique(s): cell culture | mammalian: suitable
• impurities: 1 EU/μg
• UniProt accession no.: P21781
• storage temp.: −20°C

Opis

General description

Recombinant Keratinocyte Growth Factor (KGF / FGF‑7) is supplied as a purified protein for use in mammalian cell culture research involving epithelial cell growth and differentiation studies in vitro.

Application

KGF has been used in mammalian cell culture research applications involving epithelial and keratinocyte‑related in vitro model systems.

Biochem/physiol Actions

Keratinocyte Growth Factor (FGF‑7) mediates cellular responses through fibroblast growth factor receptor pathways. KGF stimulates proliferation and differentiation of keratinocytes and other cells in the epithelium. It induces chemotaxis of microvascular endothelial cells and neovascularization of cornea. It stimulates the hyaluronic acid synthesis in proliferating and migrating basal cells. KGF contributes to the survival of cells under stress conditions.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.

Analysis Note

Determined by a cell proliferation assay using 4MBr-5 cells.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves