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Sigma-Aldrich

Myricetin

≥96.0% (HPLC)

Synonim(y):

3,3′,4′,5,5′,7-Hexahydroxyflavone, Cannabiscetin, Myricetol

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About This Item

Wzór empiryczny (zapis Hilla):
C15H10O8
Numer CAS:
529-44-2
Masa cząsteczkowa:
318.24
Beilstein:
332331
Numer WE:
208-463-2
Numer MDL:
MFCD00006827
Kod UNSPSC:
12352202
Identyfikator substancji w PubChem:
57652239
NACRES:
NA.77

Próba

≥96.0% (HPLC)

Postać

powder

mp

≥300 °C
>300 °C (lit.)

rozpuszczalność

ethanol: 10 mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow

Zastosowanie

metabolomics
vitamins, nutraceuticals, and natural products

ciąg SMILES

Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3

InChI

1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

Klucz InChI

IKMDFBPHZNJCSN-UHFFFAOYSA-N

informacje o genach

human ... CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Il4(287287) , Tnf(24835)

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Opis ogólny

Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree.

Zastosowanie

Myricetin has been used:
  • to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in rats
  • as a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP)
  • to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicans
  • as a reference standard for the quantification of phenolic compounds from Juniperus species

Działania biochem./fizjol.

Myricetin exerts anti-oxidant effects, and anti-inflammatory effects by regulating multiple signal pathways. It also displays anti-diabetic and hepatoprotective effects. Myricetin strongly inhibits yeast α-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase. It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy. Myricetin also has various nutraceuticals values and therapeutic effects.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Guilherme Roncari Rocha et al.
BMC complementary and alternative medicine, 18(1), 61-61 (2018-02-16)
Dental caries is considered a multifactorial disease, in which microorganisms play an important role. The diet is decisive in the biofilm formation because it provides the necessary resources for cellular growth and exopolysaccharides synthesis. Exopolysaccharides are the main components of
R.B. Brandt et al.
International Journal of Quantum Chemistry, 11, 195-195 (1984)
Xiaominting Song et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 134, 111017-111017 (2020-12-19)
Myricetin(MYR) is a flavonoid compound widely found in many natural plants including bayberry. So far, MYR has been proven to have multiple biological functions and it is a natural compound with promising research and development prospects. This review comprehensively retrieved
Deepak Kumar Semwal et al.
Nutrients, 8(2), 90-90 (2016-02-20)
Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals value. It is one of the key ingredients of various foods and beverages. The compound exhibits a wide range of activities that include strong anti-oxidant, anticancer, antidiabetic
M. Iio, et al.
Agricultural and Biological Chemistry, 48, 1559-1559 (1984)
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Protokoły

HPLC Analysis of Flavonoids on Ascentis® RP-Amide

Protocol for HPLC Analysis of Flavonoids on Ascentis® RP-Amide

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