M2772

Menthol

99%

• Synonim(y): 2-Isopropyl-5-methylcyclohexanol, Hexahydrothymol
• Wzór empiryczny (zapis Hilla): C₁₀H₂₀O
• Numer CAS: 89-78-1
• Masa cząsteczkowa: 156.27
• Beilstein: 3194263
• Numer WE: 201-939-0
• Numer MDL: MFCD00001484
• Kod UNSPSC: 12352212
• Identyfikator substancji w PubChem: 24896764
• NACRES: NA.25

Właściwości

• ciśnienie pary: 0.8 mmHg ( 20 °C)
• Poziom jakości: 200
• Próba: 99%
• tw: 216 °C (lit.)
• mp: 34-36 °C (lit.)
• gęstość: 0.89 g/mL at 25 °C (lit.)
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• ciąg SMILES: CC(C)C1CCC(C)CC1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
• Klucz InChI: NOOLISFMXDJSKH-UHFFFAOYSA-N
• informacje o genach: human ... TRPA1(8989) , TRPM8(79054)

Opis

Opis ogólny

Menthol (C₁₀H₂₀O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.

Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties. Menthol acts as a transient receptor potential cation channel (TRPM8) agonist. It also exhibits analgesic, antipruritic, anesthetic and cooling effects.

Zastosowanie

Menthol has been used:

• to test its antifungal susceptibility
• to determine its efficacy as an anesthetic in fish
• to activate transient receptor potential cation channel (TRPM8)
• as an odorant for measuring sniffing dynamics

Działania biochem./fizjol.

Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis. In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H315,H319
• Zwroty wskazujące środki ostrożności: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Klasyfikacja zagrożeń: Eye Irrit. 2 - Skin Irrit. 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 204.8 °F
• Temperatura zapłonu (°C): 96 °C
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves