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RPTMAG-86K

Millipore

MILLIPLEX® Rat Pituitary Magnetic Bead Panel - Endocrine Multiplex Assay

The analytes available for this multiplex kit are: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH.

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About This Item

Kod UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Design And Price Your Kit

Poziom jakości

200

reaktywność gatunkowa

rat

producent / nazwa handlowa

Milliplex®

assay range

accuracy: 75%
(GH)
accuracy: 88%
(ACTH)
accuracy: 89%
(LH)
accuracy: 90%
(TSH)
sensitivity: 0.38 pg/mL
(BDNF)
sensitivity: 0.87 pg/mL
(TSH)
sensitivity: 1.95 pg/mL
(ACTH)
sensitivity: 3.28 pg/mL
(LH)
sensitivity: 4.64 pg/mL
(Prolactin)
sensitivity: 6.50 pg/mL
(GH)
sensitivity: 7.62 pg/mL
(FSH)
standard curve range: 16-50,000 pg/mL
(GH, Prolactin)
standard curve range: 3.2-10,000 pg/mL
(ACTH, BDNF, LH, TSH)
standard curve range: 32-100,000 pg/mL
(FSH)
inter-assay cv: <20%
intra-assay cv: <10%

metody

multiplexing: suitable

metoda wykrywania

fluorometric (Luminex xMAP)

Warunki transportu

wet ice

Opis ogólny

Called the “master gland” because it controls many other endocrine glands, the pituitary secretes several key hormones that play important roles in the regulation of metabolism, growth, and reproduction. Piuitary hormones are responsible for the stimulation of the adrenal gland (ACTH), thyroid gland (TSH), ovaries and testes (FSH, LH) and breast milk production (prolactin), as well as blood pressure and the amount of water excreted by the kidneys. Through its connection with the pituitary, the hypothalamus modulates endocrine function by detecting hormone levels. Brain-Derived Neurotrophic Factor (BDNF) is a member of NGF family of neurotrophic factors which are required for differentiation and survival of specific neuronal sub-populations.

MILLIPLEX® Rat Pituitary Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in rat serum or plasma samples, rat tissue extract, or cell/tissue culture supernatant samples: Growth Hormone (GH), Thyroid-Stimulating Hormone (TSH), Adrenocorticotropic Hormone (ACTH), Luteinizing Hormone (LH), Prolactin, Follicle-Stimulating Hormone (FSH), and Brain-Derived Neurotrophic Factor (BDNF). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Endocrine

Zastosowanie

  • Analytes: Adrenocorticotropic Hormone (ACTH), Brain-Derived Neurotrophic Factor (BDNF), Follicle-Stimulating Hormone (FSH), Growth Hormone (GH), Luteinizing Hormone (LH), Prolactin, Thyroid-Stimulating Hormone (TSH)
  • Recommended Sample Type: Rat serum, plasma, cell/tissue culture supernatants or lysates
  • Recommended Sample Dilution: 25 μL per well 1:3 diluted serum or plasma; cell/tissue culture samples may require dilution in an appropriate control medium.
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Endocrine
  • Research Subcategory: Metabolism

Cechy i korzyści

Design your multiplex kit by choosing available analytes within this panel.

Informacje prawne

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
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Piktogramy

Skull and crossbonesEnvironment
GHS06,GHS09

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H302 + H332,H311,H317,H319,H411

Klasyfikacja zagrożeń

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Kod klasy składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Vivi F H Jensen et al.
Scientific reports, 10(1), 5609-5609 (2020-03-30)
Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and
Global but not gonadotrope-specific disruption of Bmal1 abolishes the luteinizing hormone surge without affecting ovulation.
Chu, A; Zhu, L; Blum, ID; Mai, O; Leliavski, A; Fahrenkrug, J; Oster, H; Boehm, U; Storch, KF
Endocrinology null
Renee N Sadowski et al.
Neurotoxicology and teratology, 42, 17-24 (2014-01-21)
Previous work has shown that exposure to bisphenol A (BPA) can affect anxiety behavior. However, no studies have examined whether administration of this endocrine disruptor during the perinatal period has the potential to induce alterations in cognitive behavior in both
Fernando Tadeu Serra et al.
Scientific reports, 9(1), 13684-13684 (2019-09-25)
Life experiences at early ages, such as physical activity in childhood and adolescence, can result in long-lasting brain effects able to reduce future risk of brain disorders and to enhance lifelong brain functions. However, how early physical exercise promotes these
Vitor Bonetti Valente et al.
Psychoneuroendocrinology, 89, 229-238 (2017-11-19)
Evidence show that stress hormones can influence cancer progression, but its role in carcinogenesis is poorly understood. In this study, we used a new method based on oral carcinogenesis model in rats to test the hypothesis that physiological levels of
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