MABN92-AF488

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 488

• Synonim(y): Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• białko sprzężone: ALEXA FLUOR^™ 488
• forma przeciwciała: purified antibody
• rodzaj przeciwciała: primary antibodies
• klon: 20A12.1, monoclonal
• reaktywność gatunkowa: human, mouse, rat
• metody: immunohistochemistry: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_001614
• numer dostępu UniProt: P55008
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... AIF1(199)

Opis

Opis ogólny

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

Zastosowanie

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

Jakość

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

Opis wartości docelowych

~17 kDa observed

Inne uwagi

Concentration: Please refer to lot specific datasheet.

Informacje prawne

ALEXA FLUOR is a trademark of Life Technologies

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable