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AQ127

Sigma-Aldrich

Goat Anti-Mouse IgG Antibody, Fc

Chemicon®, from goat

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.46

pochodzenie biologiczne

goat

Poziom jakości

białko sprzężone

unconjugated

forma przeciwciała

F(ab′)2 fragment of affinity isolated antibody

rodzaj przeciwciała

secondary antibodies

klon

polyclonal

reaktywność gatunkowa

mouse

producent / nazwa handlowa

Chemicon®

metody

ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

Powiązane kategorie

Opis ogólny

Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Specyficzność

Based on immunoelectrophoresis, the antibody reacts with the heavy chains on mouse IgG but not with the light chains on most mouse imnunoglobulins. No antibody was detected against mouse IgM, or against immunoglobulin serum proteins, but antibodies may cross-react with immunoglobulins from other species.

Immunogen

purified mouse IgG Fc fragment

Zastosowanie

Goat anti-Mouse IgG Antibody, Fc detects level of Mouse IgG & has been published & validated for use in ELISA, IP & WB.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies

Postać fizyczna

Affinity Purified F(ab′)2 Antibody in liquid buffer of 0.01% Sodium Phosphate, 0.25 M NaCl, pH 7.6 containing no preservatives.

Przechowywanie i stabilność

Store at +2 to 8°C in undiluted aliquots for up to six months, sterile conditions. Do not freeze thaw.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Sadia Samer et al.
JCI insight, 7(21) (2022-09-21)
TGF-β plays a critical role in maintaining immune cells in a resting state by inhibiting cell activation and proliferation. Resting HIV-1 target cells represent the main cellular reservoir after long-term antiretroviral therapy (ART). We hypothesized that releasing cells from TGF-β-driven
Helena de Puig et al.
Bioconjugate chemistry, 28(1), 230-238 (2017-01-18)
We investigated the effect of the protein corona on the function of nanoparticle (NP) antibody (Ab) conjugates in dipstick sandwich immunoassays. Ab specific for Zika virus nonstructural protein 1 (NS1) were conjugated to gold NPs, and another anti-NS1 Ab was
Helena de Puig et al.
Nano today, 47, 101669-101669 (2022-11-10)
Global public health infrastructure is unprepared for emerging pathogen epidemics, in part because diagnostic tests are not developed in advance. The recent Zika, Ebola, and SARS-CoV-2 virus epidemics are cases in point. We demonstrate here that multicolored gold nanoparticles, when
David E Wright et al.
Frontiers in molecular biosciences, 9, 1031756-1031756 (2022-10-29)
Over-expression of genetically encoded thioredoxin reductase 1 (TrxR1) TrxR1 can be toxic to cells due to the formation of a truncated version of the enzyme. We developed a new mammalian cell-based model to investigate TrxR1 activity. Fusion of the HIV-derived
Tarana Siddika et al.
Cells, 11(23) (2022-12-12)
Protein kinase B (AKT1) is a serine/threonine kinase and central transducer of cell survival pathways. Typical approaches to study AKT1 biology in cells rely on growth factor or insulin stimulation that activates AKT1 via phosphorylation at two key regulatory sites

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