496260

Oncostatin M, Human, Recombinant, E. coli

• Synonim(y): Oncostatin M, Human, Recombinant, E. coli
• Numer CAS: 106956-32-5
• Kod UNSPSC: 12352202
• NACRES: NA.77

Właściwości

• rekombinowane: expressed in E. coli
• Poziom jakości: 100
• Próba: ≥97% (SDS-PAGE)
• Postać: lyophilized
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• zanieczyszczenia: ≤1 EU/μg Endotoxin (EU/μg rhOSM)
• Warunki transportu: ambient
• temp. przechowywania: −70°C

Opis

Opis ogólny

Recombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Enhances the growth of both endothelial and hematopoietic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposis sarcoma cells, and a human erythroleukemic cell line, TF-1.

Recombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposi′s sarcoma cells, and human erythroleukemia cell line, TF-1.

Działania biochem./fizjol.

ED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

Lyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.

Rekonstytucja

Following reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.

Reconstitute to a final concentration of ≥10 µg/ml in sterile PBS containing ≥0.1% BSA or HSA.

Inne uwagi

Boileau, C., et al. 2000. J. Immunol.164, 5713.
Miyajima, A., et al. 2000. Cytokine Growth Factor Rev.11, 177.
Linsley, P.S., et al. 1990. Mol. Cell. Biol.10, 1882.
Kitamura, T., et al. 1989. J. Cell Physiol.140, 323.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3