850102P

16:0 Lyso PI

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

• Synonim(y): 1-hexadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(16:0/0:0; 110717
• Wzór empiryczny (zapis Hilla): C₂₅H₅₂NO₁₂P
• Numer CAS: 141553-69-7
• Masa cząsteczkowa: 589.65
• Kod UNSPSC: 51191904
• NACRES: NA.25

Właściwości

• Próba: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• Formularz: powder
• opakowanie: pkg of 1 × 100 μg (with stopper and crimp cap (850102P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850102P-500ug))
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand 850102P
• typ lipidu: phosphoglycerides
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]
• Klucz InChI: RGTDHPZXKVTZBW-OGIGPNSJSA-N

Opis

Opis ogólny

Lysophosphatidylinositol (LPI) is a bioactive lipid.[1]

Zastosowanie

16:0 Lyso PI (1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS) method conditions[2] and also has been used as lysophosphatidylinositol (LPI) substrates in lysophosphatidylinositol acyltransferase biochemical assay to assay lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes.[3] It may also be used as synthetic LPI to compare its effect with LPI from liver in transferrin (Tf)mediated endocytosis.[4]

Działania biochem./fizjol.

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) has the ability to modulate cancer cell migration. It can control the functions of endothelium.[5] LPI can serve as an autocrine regulator of cell growth, hence its known to participate in cancer progression. It can stimulate signaling cascades, that are essential for survival, migration and proliferation of cells.[1]

Opakowanie

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-500ug)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): No data available
• Temperatura zapłonu (°C): No data available