The Journal of organic chemistry, 76(9), 3551-3556 (2011-03-12)
Various fullerene-based electron acceptor materials for organic photovoltaic applications were prepared via [3+2] and [4+2] cycloadditions using a continuous flow approach. The 1,3-dipolar cycloaddition of the tosylhydrazone precursor and the Diels-Alder cycloaddition of indene to either C(60) or C(70) under
Journal of medicinal chemistry, 52(3), 675-687 (2009-01-23)
Scaffold selection involving an indole-to-indene core change led to the discovery of a series of indenylsulfonamides that act as 5-HT6 serotonin receptor agonists. The variety of the targeted ligands and their synthetic complexity required multistep synthetic approaches. The novel indenylsulfonamides
Prompted by our discovery of a new class of conformationally-locked indeno[2,1-c]quinolines as anti-mycobacterials, compounds 2a and 3a (Fig. 1; MIC < 0.39 μg mL(-1) and 0.78 μg mL(-1), respectively)(14) with a freely rotating C2-imidazolo substituent, we herein describe the synthesis
Journal of the American Chemical Society, 132(2), 807-815 (2009-12-19)
The chemical features, such as substrate stability, product distribution, and substrate generality, and the reaction mechanism of Brønsted superacid-catalyzed cyclization reactions of aromatic ring-containing acetoacetates (beta-ketoesters) were examined in detail. While two types of carbonyl cyclization are possible, i.e., keto
Applied microbiology and biotechnology, 85(4), 995-1004 (2009-07-02)
The styAB genes from Pseudomonas putida CA-3, which encode styrene monooxygenase, were subjected to three rounds of in vitro evolution using error-prone polymerase chain reaction with a view to improving the rate of styrene oxide and indene oxide formation. Improvements
Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.
