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P2RX1

purinergic receptor P2X, ligand-gated ion channel, 1

Synonimy:
P2X1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5023) Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
  • Mouse(18436) purinergic receptor P2X, ligand-gated ion channel, 1
  • Rat(25505) purinergic receptor P2X, ligand-gated ion channel, 1
  • Domestic Rabbit(100350587) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic cat(101091060) purinergic receptor P2X, ligand-gated ion channel, 1
  • Horse(100060689) purinergic receptor P2X, ligand-gated ion channel, 1
  • cow(514898) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic guinea pig(100727772) purinergic receptor P2X, ligand-gated ion channel, 1
  • sheep(101101902) purinergic receptor P2X, ligand-gated ion channel, 1
  • Zebrafish(387296) purinergic receptor P2X, ligand-gated ion channel, 1
  • chicken(395190) purinergic receptor P2X, ligand-gated ion channel, 1
  • dog(491223) purinergic receptor P2X, ligand-gated ion channel, 1
  • naked mole-rat(101722936) purinergic receptor P2X, ligand-gated ion channel, 1

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
α,β-Methyleneadenosine 5′-triphosphate lithium salt, ≥93% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Reactive Blue 4, Dye content 35 %,
Gatunek
rat
NF 023 hydrate, ≥98% (HPLC), solid,
Gatunek
human
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-P2RX1 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
dog, horse, human
Zastosowanie
immunohistochemistry
western blot
Anti-P2RX1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-P2Rx1 wytwarzane u królików, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-P2X1 Purinergic Receptor antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Suramin sodium salt, ≥98% (TLC),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse P2rx1,
Gatunek
mouse
MISSION® esiRNA, targeting human P2RX1,
Gatunek
human