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MTNR1A

melatonin receptor 1A

Synonimy:
MEL-1A-R, MT1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
6-Hydroxymelatonin, ,
Gatunek
human
Ramelteon, ,
Gatunek
human
Agomelatine, ≥98% (HPLC),
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Luzindole, ≥90%,
Gatunek
human
Agomelatine, ≥98% (HPLC),
Gatunek
human
Melatonin, powder, ≥98% (TLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Melatonin, powder, ≥98% (TLC),
Gatunek
human

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
N-Acetyl-5-hydroxytryptamine, ≥99% (HPLC), powder,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
ChemiSCREEN Membrane Preparation Recombinant Human MT1 Melatonin Receptor, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MTNR1A,
Gatunek
human