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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Synonimy:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2

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ELISA

Numer produktu
Opis
Gatunek
Rat MMP-2 ELISA, for serum, plasma and cell culture supernatants,
Gatunek
rat
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Gatunek
mouse
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MMP-2 Antibody, catalytic domain, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunoprecipitation (IP)
western blot
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
Reaktywność gatunkowa
bovine, human, mouse, rat
Zastosowanie
Anti-MMP-2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-MMP2, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rat, sheep
Zastosowanie
immunohistochemistry
western blot
Anti-MMP-2 Antibody, pro and active form, clone VB3, clone VB3, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
CP-471474, ≥98% (HPLC),
Gatunek
human, rat, mouse
Marimastat, ≥98% (HPLC),
Gatunek
human, rat, mouse
CP-101537, ≥98% (HPLC),
Gatunek
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
MMP-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Gatunek
human
Matrix Metalloproteinase-2 human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Gatunek
human
Matrix Metalloproteinase-2 from mouse, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
mouse, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MMP2,
Gatunek
human
MISSION® esiRNA, targeting mouse Mmp2,
Gatunek
mouse