Przejdź do zawartości
Merck

CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

Synonimy:
CAMKA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
  • Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
  • Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
  • Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
  • Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
  • dog(612941) calcium/calmodulin-dependent protein kinase II alpha
  • domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha
  • cow(530719) calcium/calmodulin-dependent protein kinase II alpha
  • naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
  • domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
  • Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
  • chicken(374175) calcium/calmodulin-dependent protein kinase II alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CAMK2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anty-CAMK2A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-CAMK2A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anty-CAMK2A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Przeciwciało przeciwko kinazie CaM II, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
bovine, chicken, guinea pig, hamster, human, mouse, rabbit, rat
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Gatunek
human, rat, mouse
Adenine, ≥99%,
Gatunek
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
CAMK2α, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
Calmodulin-dependent Protein Kinase II fragment 290-309, ≥97% (HPLC),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CAMK2A,
Gatunek
human
MISSION® esiRNA, targeting mouse Camk2a,
Gatunek
mouse

Small Molecule - Substrate

Numer produktu
Opis
Gatunek
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Gatunek
mouse, rat, human