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Merck

PHR1235

Supelco

视黄醇(维生素A)棕榈酸酯 CRM

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

维生素A棕榈酸酯, 全−反式−视黄醇棕榈酸酯, 维生素 A 棕榈酸酯

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About This Item

经验公式(希尔记法):
C36H60O2
CAS号:
分子量:
524.86
Beilstein:
1917366
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
价格与库存信息目前不能提供

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to USP 1602502

API类

retinyl compounds

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

用于质量控制的制药二级认证标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
棕榈酸视黄酯属于一种类视黄醇,化学上类似于维生素A。它对视力、皮肤和免疫功能都有益处,还能抑制细胞增殖和预防癌症。它是重要的膳食和治疗性化合物。[1]

应用

棕榈酸视黄酯可用作药物参考标准品,通过色谱[2]和分光光度[3]技术对药物制剂中的分析物进行测定。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

生化/生理作用

评论:维生素 A 代谢。

分析说明

这些次级标准为 USP、EP(PhEur)和 BP 基本标准提供了多种可追溯性。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

要查看此材料的分析证书样本,请在下框中输入LRAB3694。这只是一个示例证书,可能与您收到的批次不符。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Aquatic Chronic 3 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

闪点(°F)

No data available

闪点(°C)

No data available


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Vitamin A Palmitate-β-cyclodextrin inclusion complexes: Characterization, protection and emulsification properties
Vilanova N and Solans C
Food Chemistry, 175(1-2), 529 -5535 (2015)
Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography -atmospheric pressure chemical ionization -mass spectrometry
van Breemen RB, et al.
Journal of Chromatography A, 794(1-2), 245-251 (1998)
S Pedersen-Bjergaard et al.
Journal of chromatography. A, 876(1-2), 201-211 (2000-05-24)
Microemulsion electrokinetic chromatography (MEEKC) was carried out in a pH 2.5 phosphate buffer to effectively suppress the electroosmotic flow (EOF). With 66.6% (w/w) 25 mM phosphate buffer pH 2.5, 20.0% (w/w) 2-propanol, 6.6% (w/w) 1-butanol, 6.0% (w/w) sodium lauryl sulphate
I J Martins et al.
Biochimica et biophysica acta, 1081(3), 328-338 (1991-02-05)
There are inverse relationships between HDL cholesterol and plasma triacylglycerol concentrations in normal and in hypertriglyceridemic individuals. To investigate the interactions between triacylglycerol-rich lipid particles and HDL, a lipid emulsion model of the triacylglycerol-rich lipoproteins was prepared. When emulsion particles
Eliot L Berson et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 130(6), 707-711 (2012-02-15)
To evaluate whether a diet high in long chain ω-3 fatty acids can slow the rate of visual acuity loss among patients with retinitis pigmentosa receiving vitamin A palmitate. We calculated dietary intake from questionnaires completed annually by 357 adult

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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