跳转至内容
Merck
所有图片(1)

文件

N9890

Supelco

诺氟沙星

analytical standard, ≥98% (TLC)

别名:

1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸, 1-乙基-6-氟-1,4-二氢-4-氧代-7-哌嗪-3-喹啉羧酸

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C16H18FN3O3
CAS号:
70458-96-7
分子量:
319.33
EC號碼:
274-614-4
MDL號碼:
MFCD00079532
分類程式碼代碼:
41116107
PubChem物質ID:
329818696
NACRES:
NA.24

等級

analytical standard

品質等級

200

agency

EPA 1694

化驗

≥98% (TLC)

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

clinical testing

格式

neat

儲存溫度

2-8°C

SMILES 字串

CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3

InChI

1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

InChI 密鑰

OGJPXUAPXNRGGI-UHFFFAOYSA-N

基因資訊

human ... CYP1A2(1544)
rat ... Gabra1(29705)

正在寻找类似产品? 访问 产品对比指南

相关类别

一般說明

化学结构式：氟喹诺酮类
诺氟沙星 (Norfloxacin) 是一种广谱抗菌药物，对多种革兰氏阳性菌和阴性菌均有抗菌活性。

應用

参考产品的检验报告，了解更多关于合适仪器技术的信息。联系技术服务部寻求进一步支持。
诺氟沙星可作为标准品使用荧光分光光度法测定人血清样品中的诺氟沙星。

生化／生理作用

诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶（拓扑异构酶）复合物的结构转换而阻断 DNA 复制。
操作方式：抑制细菌 DNA 复制
抗菌谱：革兰氏阴性菌； 对革兰氏阳性菌效果较差

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
0000249279
0000227061
0000249280
SLCQ1196
0000185003

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

L M Cavaco et al.
Journal of clinical microbiology, 47(9), 2751-2758 (2009-07-03)
Fluoroquinolone resistance in members of the Enterobacteriaceae family is mostly due to mutations in the quinolone resistance-determining regions of the topoisomerase genes. However, transferable genes encoding quinolone resistance have recently been described. The current methods for susceptibility testing are not
Fluorescence reaction and complexation equilibria between norfloxacin and aluminium (III) ion in chloride medium
Djurdjevic.TP, et al.
Analytica Chimica Acta, 300, 253-259 (1995)
Deepika Sharma et al.
European journal of medicinal chemistry, 44(6), 2347-2353 (2008-10-15)
In the present study, we have synthesized 2-(substituted phenyl)-1H-imidazole (1-12) and (substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13-26) analogues and screened them for their antimicrobial activity against gram positive, gram negative and fungal species. The results of antibacterial study indicated that compounds 15
Anita Reinhardt et al.
Antimicrobial agents and chemotherapy, 51(4), 1341-1350 (2007-01-31)
Intubated patients frequently become colonized by Pseudomonas aeruginosa, which is subsequently responsible for ventilator-associated pneumonia. This pathogen readily acquires resistance against available antimicrobials. Depending on the resistance mechanism selected for, resistance might either be lost or persist after removal of
Kristine H Wammer et al.
Water research, 47(1), 439-448 (2012-11-13)
Fluoroquinolone (FQ) antibacterial compounds are frequently detected in the aquatic environment, and photodegradation is expected to play an important role in FQ fate in some sunlit surface waters. This study investigated the direct aquatic photochemistry of three FQs: norfloxacin, ofloxacin
查看所有相关文献

商品

Inhibition of Nucleic Acid Synthesis by Antibiotics

Quinolones are a key group of antibiotics that interfere with DNA synthesis by inhibiting topoisomerase, most frequently topoisomerase II (DNA gyrase), an enzyme involved in DNA replication.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门