推荐产品
生物来源
synthetic
质量水平
方案
≥98%
表单
powder
mp
227-229 °C (lit.)
溶解性
chloroform: 50 mg/mL
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
CCN1C=C(C(O)=O)C(=O)c2ccc(C)nc12
InChI
1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)
InChI key
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
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一般描述
化学结构：喹诺酮
应用
用于调节（抑制）细菌DNA促旋酶依赖性过程，如DNA聚合、（ATP依赖性）tDNA超螺旋化和染色体断裂。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Lucia Pallecchi et al.
Antimicrobial agents and chemotherapy, 51(8), 2720-2725 (2007-06-06)
A survey carried out in 2005 among members of a healthy population of children living in Bolivia and Peru revealed that fecal carriage of Escherichia coli strains resistant to expanded-spectrum cephalosporins was remarkably increased compared to that observed in the
Inna Chmelnitsky et al.
Antimicrobial agents and chemotherapy, 52(8), 2962-2965 (2008-06-04)
Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and bla(KPC-2) genes encoded on the same plasmid. One isolate also carried the aac(6')-Ib-cr gene. Coexistence of quinolone resistance determinants and bla(KPC-2) on the same plasmid
Valeria Bortolaia et al.
Antimicrobial agents and chemotherapy, 54(4), 1623-1626 (2010-01-27)
We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime or ceftiofur obtained from healthy broilers housed in five Italian farms. The bla(CTX-M-1), bla(CTX-M-32) and bla(SHV-12) beta-lactamase genes were identified on IncI1, IncN, or IncFIB plasmids. Considerable genetic diversity
Suzanne Bialek et al.
Antimicrobial agents and chemotherapy, 54(10), 4373-4378 (2010-08-04)
Cross-resistance to cefoxitin (FOX), chloramphenicol (CMP), and quinolones (nalidixic acid [NAL]) related to a putative efflux system overexpression has recently been reported for Klebsiella pneumoniae. The potential impact of this multidrug resistance (MDR) on the virulence of K. pneumoniae was
Kate S Baker et al.
The Lancet. Infectious diseases, 15(8), 913-921 (2015-05-06)
Shigellosis is an acute, severe bacterial colitis that, in high-income countries, is typically associated with travel to high-risk regions (Africa, Asia, and Latin America). Since the 1970s, shigellosis has also been reported as a sexually transmitted infection in men who
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