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Merck

39405

Sigma-Aldrich

4-(二甲氨基)吡啶

purum, ≥98.0% (NT)

别名:

N,N-二甲基-4-吡啶胺, DMAP

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About This Item

经验公式(希尔记法):
C7H10N2
CAS号:
分子量:
122.17
Beilstein:
110354
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22
价格与库存信息目前不能提供

等级

purum

质量水平

方案

≥98.0% (NT)

表单

crystals
pellets

mp

108-110 °C (lit.)
111-114 °C

溶解性

methanol: 0.1 g/mL, clear, colorless to almost colorless

官能团

amine

SMILES字符串

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChI key

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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一般描述

4-(二甲基氨基)吡啶通常用作胺、醇、烯醇化物和酚的酰化催化剂。它也可用于羧酸的酯化。众所周知,它在非极性溶剂中有良好的催化活性。[1]

应用

4-(二甲基氨基)吡啶可用于:
  • 作为水溶性金纳米颗粒制备中的封端剂[2]
  • 作为环氧单体聚合的引发剂[3]
  • 作为无电镀制备催化用金纳米颗粒的助剂[4]
  • 通过γ,δ-不饱和羧酸的碘内酯化制备γ-和δ-内酯的催化剂。[5]

酰化反应的高效催化剂

其他说明

超亲核酰化催化剂。综述[6][7][8]

警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

靶器官

Nervous system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

255.2 °F

闪点(°C)

124 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

E.F. Scriben
Chemical Society Reviews, 13, 129-129 (1983)
A. Hassner
Tetrahedron, 34, 2069-2069 (1978)
Assessment of 4-(dimethylamino) pyridine as a capping agent for gold nanoparticles
Gandubert VJ and Lennox RB
Langmuir, 21(14), 6532-6539 (2005)
4-(Dimethylamino) pyridine-catalysed iodolactonisation of γ, δ-unsaturated carboxylic acids
Meng C, et al.
Organic & Biomolecular Chemistry, 13(24), 6766-6772 (2015)
Homopolymerization of epoxy monomers initiated by 4-(dimethylamino) pyridine
Dell'Erba IE and Williams RJ
Polym. Eng. Sci., 46(3), 351-359 (2006)

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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