This product is not prepared for cell culture applications.
Please see the following products below which are tested for cell culture use:
https://www.sigmaaldrich.com/product/sigma/d4902
https://www.sigmaaldrich.com/product/sigma/d2915
推荐产品
等級
certified reference material
品質等級
形狀
liquid
特點
Snap-N-Spike®/Snap-N-Shoot®
包裝
ampule of 1 mL
製造商／商標名
Cerilliant®
濃度
1.0 mg/mL in methanol
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
clinical testing
形式
single component solution
儲存溫度
−20°C
SMILES 字串
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI 密鑰
UREBDLICKHMUKA-CXSFZGCWSA-N
基因資訊
human ... NR3C1(2908)
一般說明
地塞米松是一种强效糖皮质激素，可作为抗炎和免疫抑制剂，用于治疗许多炎症和自身免疫性疾病，肿瘤学和内分泌疾病（例如Addison′s病）。通过LC-MS/MS测定血清或血浆中的地塞米松水平，用于地塞米松抑制试验或监测地塞米松治疗方案。该经认证的加标溶液®适合用作制备LC-MS/MS法检测地塞米松的校准品和质控品的起始物料。
應用
- 受控药物传输系统。含有地塞米松的水凝胶显微操作针表现出程序化中间相转变，优化了治疗应用中药物的控制释放。药物递送技术的这一进步说明了地塞米松溶液在创新药物材料开发中的实用性（Dawud et al., 2024）。
- 增强的鼻腔给药：结合地塞米松的牛血清白蛋白纳米颗粒是一种用于增强鼻腔给药的新型凝胶系统。这项研究强调了地塞米松溶液在创造更有效、对患者友好的药物递送方式方面的潜力（Mardikasari et al., 2023）。
- 缓释制剂通过同轴微流体系统持续释放地塞米松的聚乙烯醇微粒的开发表明，地塞米松溶液在提高治疗效果和患者依从性的精确药物递送系统的生产中起到关键作用（Abdi Majareh et al., 2023）。
- 眼部疾病的局部药物递送：研究人员开发了负载地塞米松的壳聚糖纳米颗粒，用于内毒素诱导的葡萄膜炎兔模型中的局部施用，这表明使用地塞米松溶液的局部给药系统取得了重大进展。该应用特别适用于炎症性眼病的治疗，可提高药物递送效率（Alkholief et al., 2023）。
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相關產品
产品编号
说明
价格
氢化可的松-D4标准液 CRM 溶液, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
11-脱氧皮质醇-D5标准液 CRM, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
17α-羟孕酮-13C3标准液 溶液, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes,Central nervous system
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
49.5 °F - closed cup
閃點（°C）
9.7 °C - closed cup
其他客户在看
Erich Piovan et al.
Cancer cell, 24(6), 766-776 (2013-12-03)
Glucocorticoid resistance is a major driver of therapeutic failure in T cell acute lymphoblastic leukemia (T-ALL). Here, we identify the AKT1 kinase as a major negative regulator of the NR3C1 glucocorticoid receptor protein activity driving glucocorticoid resistance in T-ALL. Mechanistically
Shankar Swaminathan et al.
Journal of biomedical nanotechnology, 9(6), 998-1007 (2013-07-19)
Nanosponges (NS) were synthesized by crosslinking of beta cyclodextrins with diphenyl carbonate. It is a hyper-branched polymer with an ultra high encapsulation efficiency leading to formation of colloidal systems. Dexamethasone (DEX) on the other hand is a poorly soluble drug
María-Victoria Mateos et al.
The New England journal of medicine, 369(5), 438-447 (2013-08-02)
For patients with smoldering multiple myeloma, the standard of care is observation until symptoms develop. However, this approach does not identify high-risk patients who may benefit from early intervention. In this randomized, open-label, phase 3 trial, we randomly assigned 119
Valentina Proserpio et al.
Genes & development, 27(11), 1299-1312 (2013-06-12)
Elucidating the epigenetic mechanisms underlying muscle mass determination and skeletal muscle wasting holds the potential of identifying molecular pathways that constitute possible drug targets. Here, we report that the methyltransferase SMYD3 modulates myostatin and c-Met transcription in primary skeletal muscle
Peter Bärtsch et al.
The New England journal of medicine, 368(24), 2294-2302 (2013-06-14)
A 45-year-old healthy man wishes to climb Mount Kilimanjaro (5895 m) in a 5-day period, starting at 1800 m. The results of a recent exercise stress test were normal; he runs 10 km 4 or 5 times per week and
-
Is this formulation prepared for cell culture applications ?
1 answer-
Helpful?
-
Active Filters
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门
