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Merck

G6600

Sigma-Aldrich

甘氨酸甲酯 盐酸盐

99%, for peptide synthesis

别名:

Glycine methyl ester·HCl, Methyl glycinate hydrochloride

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About This Item

线性分子式:
NH2CH2COOCH3 · HCl
CAS号:
分子量:
125.55
Beilstein:
3593644
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.22

product name

甘氨酸甲酯 盐酸盐, 99%

化驗

99%

形狀

powder, crystals or chunks

反應適用性

reaction type: solution phase peptide synthesis

顏色

white

mp

175 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

Cl.COC(=O)CN

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H

InChI 密鑰

COQRGFWWJBEXRC-UHFFFAOYSA-N

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一般說明

甘氨酸甲酯盐酸盐又名甲基甘氨酸酯盐酸盐,是一种甘氨酸衍生物,用于制备氨基酸和有机化合物。

應用

甘氨酸甲酯盐酸盐可用于合成以氨基酸酯为侧链的环磷腈类物质。还可在水相中合成多肽,是一种绿色的制肽法。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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The investigation of thermosensitive properties of phosphazene derivatives bearing amino acid ester groups
A Uslu
Journal of Molecular Structure, 1136, 90-99 (2017)
A green protocol for peptide bond formation in WEB
M Konwar
Tetrahedron Letters, 57, 2283-2285 (2016)
D Levy
Biochimica et biophysica acta, 317(2), 473-481 (1973-08-30)
A procedure has been described for the modification of the amino group of glycine methyl ester, and the amino groups of the hormone, insulin, with the reagent p-nitrophenyl-p-chloromercuribenzoate, effecting the introduction of the chloromercuri group at various defined sites in
K W Kuo et al.
International journal of peptide and protein research, 46(2), 181-185 (1995-08-01)
To study the functional involvements of the common interaction of the Leu-1 alpha-amino group and Asp-58 in cobrotoxin, the lysine epsilon-amino groups of cobrotoxin were initially guanidinated with o-methylisourea. The alpha-amino group of Leu-1 was them modified with TNBS after
L K Frankel et al.
Biochemistry, 38(43), 14271-14278 (1999-11-26)
The effects of the modification of carboxylate groups on the manganese-stabilizing protein of photosystem II were investigated. Carboxylate groups (including possibly the C-terminus) on the manganese-stabilizing protein were modified with glycine methyl ester in a reaction facilitated by 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. The

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