907286

H-L-Photo-Proline hydrochloride

≥95%, for peptide synthesis

• 别名: (S)-1,2,5-Triazaspiro[2.4]hept-1-ene-6-carboxylic acid, Diazirine amino acid, Photo-Pro, Photo-crosslinking amino acid, Photoprobe building block
• 经验公式（希尔记法）: C₅H₈ClN₃O₂
• 分子量: 177.59
• 分類程式碼代碼: 12352101
• NACRES: NA.22

属性

• product name: H-L-Photo-Proline hydrochloride, ≥95%
• 化驗: ≥95%
• 形狀: powder
• 反應適用性: reaction type: solution phase peptide synthesis
• 應用: peptide synthesis
• 儲存溫度: −20°C

说明

應用

H-L-Photo-Proline HCl is a diazirine-containing proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907324.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

其他說明

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable