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Merck

446327

Sigma-Aldrich

N-Boc-L-脯氨醇

98%

别名:

(S)-1-Boc-2-吡咯烷甲醇

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About This Item

经验公式(希尔记法):
C10H19NO3
CAS号:
分子量:
201.26
Beilstein:
3542667
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

solid

光學活性

[α]21/D −48°, c = 1.3 in chloroform

反應適用性

reaction type: Boc solid-phase peptide synthesis

mp

62-64 °C (lit.)

應用

peptide synthesis

SMILES 字串

CC(C)(C)OC(=O)N1CCC[C@H]1CO

InChI

1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h8,12H,4-7H2,1-3H3/t8-/m0/s1

InChI 密鑰

BFFLLBPMZCIGRM-QMMMGPOBSA-N

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應用

用于合成抗凝剂。
用于新型烟碱型乙酰胆碱受体配体(具有强化识别性)的结构单元。用于合成手性 β-氨基硫醚和 β-氨基硫醇。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Elliott, R.L. et al.
Bioorganic & Medicinal Chemistry Letters, 6, 2283-2283 (1996)
Matthias Schulz et al.
Physical chemistry chemical physics : PCCP, 19(10), 6996-7008 (2017-02-28)
We suggest and explore a novel route towards organic photodetectors sensitive to the circular polarization state of light. For this, we insert fullerene-blended thin films of homochiral squaraine compounds acting as a highly circular dichroic active layer into conventional bulk
N H Lin et al.
Journal of medicinal chemistry, 40(3), 385-390 (1997-01-31)
2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine, ABT-089 (S-4), a member of the 3-pyridyl ether class of nicotinic acetylcholine receptor (nAChR) ligands, shows positive effects in rodent and primate models of cognitive enhancement and a rodent model of anxiolytic activity and possesses a reduced propensity to
Cran, G.A. et al.
Tetrahedron Asymmetry, 6, 1553-1553 (1995)
Satoshi Komoriya et al.
Bioorganic & medicinal chemistry, 12(9), 2099-2114 (2004-04-15)
Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-amidino-2-naphthyl)propanoic acid hydrochloride pentahydrate (DX-9065a) was previously found in our laboratory

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